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Cubicin Injection is a prescription antibiotic indicated for the treatment of bacterial infections caused by specific types of Gram-positive bacteria. It contains FDA-approved Daptomycin as the active ingredient and is commonly prescribed for severe cases that need hospital care. Daptomycin belongs to the class of Cyclic Lipopeptide Antibiotics. Norvatis India Ltd, a GMP-certified facility, manufactures this product.
It works by attaching to bacterial cell membranes and creating pores, which cause the bacteria to lose essential ions and die rapidly. It is effective against tough infections like Methicillin-Resistant Staphylococcus Aureus (MRSA), mainly used for complicated skin infections and Staphylococcus Aureus bloodstream infections, including right-sided Endocarditis.
Cubicin must be prepared by mixing the 350 mg vial with 7 mL of sterile water and then diluting it in 50 mL of normal saline. It is given as an IV infusion over 30 minutes once daily. The usual dose is 4 mg/kg for skin infections and 6 mg/kg for bloodstream infections, with adjustments for kidney problems.
Common side effects of Cubicin350 mg Injection are nausea, diarrhea and headache. Overdose may raise Creatine Phosphokinase (CPK) levels or cause muscle-related problems. In such cases, the doctor may pause the treatment and provide supportive care until levels return to normal. For a missed dose, take it as soon as you remember, unless it’s almost time for the next one.
Precautions include regularly checking CPK levels, especially if you take statins or fibrates, and exercising caution if you have kidney or liver problems. Avoid using Cubicin Injection for Pneumonia, and monitor International Normalized Ratio (INR) levels if it is taken with Warfarin.
Store vials at 2-8°C (36-46°F). After mixing, the solution stays stable for 12 hours at room temperature or 48 hours in the fridge.
Cubicin 350 mg Injection offers a reliable treatment for severe gram-positive bacterial infections, particularly those caused by resistant strains, such as MRSA. Key benefits include:
This Daptomycin injection must be used only under the guidance of a qualified healthcare professional. General instructions include:
Currently, Cheap Medicine Shop does not offer additional strengths or same-salt substitutes for Cubicin Injection. However, other antibiotic treatments can meet your treatment requirements. Always consult a healthcare professional before choosing an alternative to make sure it is safe and suitable for your specific condition.
| Frastim 300 mcg Injection | $175.31/Injection |
| Filgen 300 mcg Injection | $155.75/Injection |
Like any medicine, this Cubicin Injection may cause specific side effects, including:
These effects are usually mild and temporary, often improving as your body adjusts to the treatment. If they continue or worsen, contact your healthcare provider immediately.
Liver Disease
Patients with mild to moderate liver dysfunction can use this medication with no possible dose adjustments. However, limited studies are available for severe hepatic impairment, so caution is advised.
Kidney Impairment
Patients with kidney impairment should take Cubicin Injection with caution, as the accumulation of Daptomycin due to slow clearance can lead to an increased risk of side effects. There can be possible adjustments to your dose.
Pregnant and Breastfeeding women
Limited information is available for pregnancy, so caution is advised. When it comes to breastfeeding, small amounts may pass into breast milk, but limited information is available on its effects on breastfed infants.
Avoid
Avoid the medication if you are allergic to Daptomycin. There is no well-defined interaction between Cubicin and alcohol. However, consuming alcohol is generally discouraged, especially in sick or hospitalized patients.
No, Daptomycin is not available in an oral form. It is administered only as an intravenous (IV) injection because it is not absorbed effectively when taken orally. It must be administered under the supervision of a medical professional.
No, Cubicin is not considered a last-resort antibiotic. But, it is reserved for moderate to severe infections caused by gram-positive bacteria, particularly those resistant to treatment, such as MRSA.
No, Daptomycin and Vancomycin are different antibiotics. Vancomycin is a Glycopeptide that blocks cell-wall synthesis, while Daptomycin is a lipopeptide that disrupts bacterial membranes. Vancomycin is typically the first-line treatment, and when it fails or patients cannot tolerate it, doctors prescribe Daptomycin.
No, Cubicin is not meant for indefinite long-term use. However, it may be administered for several weeks, often up to 6 weeks, for conditions such as bacteremia or Endocarditis, when required for serious infections under strict medical supervision.
No, Daptomycin is not considered a high-risk or high-alert medication like chemotherapy drugs or vasopressors. However, it still requires close monitoring because it can cause specific side effects, particularly muscle and kidney-related issues.
Cubicin doesn’t remain in the body for a long time. In adults with normal kidney function, its half-life is about 8-9 hours. It means most of the medicine is cleared within 1.5-2 days after the last dose.
Some of the most challenging bacterial infections to treat are caused by drug-resistant bacteria, such as MRSA, Vancomycin-resistant Enterococcus (VRE), and certain multidrug-resistant Gram-negative bacteria. These infections often require strong, targeted antibiotics and careful medical supervision.
