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Dapanorm Trio Tablet ER
What is Dapanorm Trio
Dapanorm Trio Tablet ER is an oral antidiabetic medicine for managing Type 2 Diabetes Mellitus in patients, particularly adults. It comprises three FDA-approved active ingredients: Dapagliflozin (a Sodium-Glucose Cotransporter 2 inhibitor), Metformin (a Biguanide), and Sitagliptin (a Dipeptidyl Peptidase-4 inhibitor). Alkem Laboratories Ltd manufactures the product.
Dapagliflozin blocks glucose reabsorption in the kidneys, increasing glucose excretion in urine and lowering blood sugar levels. Metformin lowers glucose production in the liver, improving the body's response to Insulin. At the same time, Sitagliptin increases Insulin release and decreases sugar production by the liver by enhancing incretin hormone activity. This combination provides a comprehensive approach to blood sugar regulation in Type 2 Diabetes Mellitus.
This medication's most common side effects include upper respiratory infections, urinary tract infections, and sore throats. Drinking lots of fluids and maintaining good hygiene can help prevent these symptoms. Some may also experience low blood sugar levels (Hypoglycemia) and Lactic Acidosis if the medication is taken alongside other antidiabetic medicines, mainly due to the Metformin component. Alcohol can increase the chance of contracting side effects. Other significant interactions include liver and kidney disease.
Patients should inform their doctors of their medications to prevent complications. They should never skip out on the medication unless the doctor says so. Maintaining a better lifestyle and monitoring blood glucose levels regularly is crucial for better Diabetes management.
What are the benefits of taking Dapanorm Trio
It combines three effective antidiabetic agents, Dapagliflozin, Metformin, and Sitagliptin, to better manage blood glucose levels in patients with Type 2 Diabetes Mellitus.
- It helps lower blood sugar levels in adults with Type 2 Diabetes Mellitus, especially when diet, exercise, or single-drug therapy cannot control glucose.
- It combines Dapagliflozin, Metformin, and Sitagliptin, which work together to remove excess glucose through urine, lower the liver's glucose production, improve Insulin sensitivity, and enhance Insulin release.
- Regular use of this medication improves overall glycemic control, reduces HbA1c levels, and can help prevent serious Diabetes complications such as kidney damage, nerve problems, and vision loss.
- The Dapagliflozin component may also support mild weight loss by promoting glucose excretion in urine.
How to take Dapanorm Trio
It is a prescription-based medication that patients should take according to the doctor's instructions. Here are some general guidelines for this medication.
- Take the dose as prescribed by your doctor.
- It can be taken with or without food.
- Swallow the whole tablet with water. Do not crush or chew it.
- Take the tablet at a fixed time daily for better results.
Strengths and Substitutes
No strengths of Dapanorm Trio are available at Cheap Medicine Shop. However, substitutes with the same salts are available.
| Sitahenz-DM 500 Tablet 500 ER | $8.40/10 Tablets |
| Sitared-MD XR 1000 Tablet | $7.90/10 Tablets |
| Sitared-MD XR 500 Tablet | $7/10 Tablets |
View all substitutes for Diabetes
What are the side effects of Dapanorm Trio
Its side effects are mild and will subside as the body adjusts to the medication. However, if the symptoms continue or worsen, consult a doctor immediately.
- Urinary tract infections
- Nausea
- Vomiting
- Headache
- Coughing
Safety Advice
Liver disease
The medication is not generally recommended for patients with liver disease. It is due to the risk of serious side effects, particularly lactic acidosis, which is associated with the Metformin component. Consult your doctor for appropriate treatment.
Kidney impairment
Using the medication is generally safe for patients with mild to moderate kidney impairment. However, as a precautionary measure, consult a doctor. Patients with severe kidney dysfunction should not use this medication because the risk of serious side effects, mainly Lactic Acidosis from the metformin component, is significantly increased.
Pregnancy and breastfeeding
Dapanorm trio is not generally recommended during pregnancy due to limited data available to determine the adverse effects on the fetus. Patients should consult a doctor to weigh the benefits and risks. Similarly, due to limited data about the salts' excretion into the milk, nursing mothers should consult a doctor for appropriate medication.
Avoid
Avoid taking the medication if you are allergic to Dapagliflozin, Metformin, and Sitagliptin. Alcohol can heighten the risks of side effects, which patients should also avoid. Driving is not usually affected while taking the medication, but caution is still necessary.
FAQs
How long does it take for the Dapanorm trio to work?
Dapanorm Trio usually lowers blood sugar shortly after beginning treatment, though the response time can vary between individuals. Some may see improvements within a few days. Still, the full benefits, like better HbA1c levels and stable daily glucose, typically appear after several weeks of regular use alongside a complete Diabetes care plan.
Can I stop taking Dapanorm Trio if I feel better?
No, you should not stop taking Dapanorm Trio just because you feel better. Discontinuing the medication without your doctor's guidance can cause your blood glucose levels to increase, raising the chance of getting of serious complications such as kidney damage and blindness.
What will happen if I overdose on Dapanorm Trio?
Overdosing can lead to several severe symptoms and requires immediate medical attention. Common signs of overdose include low blood sugar (hypoglycemia), severe nausea, vomiting, stomach pain, dizziness, and anxiety. In severe cases, overdose may cause Lactic Acidosis.
What are the symptoms of Lactic Acidosis?
The symptoms of Lactic Acidosis include feeling unusually cold or generally uncomfortable, severe nausea or vomiting, persistent stomach or abdominal pain, unexplained weight loss, muscle cramps, rapid or difficult breathing, severe tiredness or weakness, reduced body temperature, and a slow heartbeat. Consult a doctor immediately if you experience any of these symptoms.
Is Dapagliflozin good for the heart?
Yes, Dapagliflozin is considered beneficial for the heart, especially in people with Type 2 Diabetes Mellitus and heart failure. Clinical studies have shown that Dapagliflozin reduces the risk of cardiovascular death, heart failure hospitalizations, and all-cause mortality in a broad range of heart failure patients, including those without diabetes.