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Dpressin Nasal Spray
What is Dpressin Nasal Spray
Dpressin Nasal Spray is a synthetic antidiuretic medication used to treat Diabetes Insipidus, bedwetting (nocturnal enuresis), and certain types of increased urination and thirst. Its primary ingredient is Desmopressin Acetate, a synthetic analog of the natural human hormone Vasopressin (antidiuretic hormone).
Dpressin reduces urine production by increasing water reabsorption in the kidneys. Side effects of Dpressin may include nasal irritation, headache, nausea, and, in rare cases, Hyponatremia (low sodium levels). The medication should be stored at room temperature (15°C-25°C), away from direct light and moisture, with the bottle kept upright.
United Biotech Pvt Ltd is the leading manufacturer of Dpressin Nasal Spray. This medication requires careful dosing and monitoring to prevent water retention and electrolyte imbalance, especially when treatment begins.
What are the benefits of Dpressin Nasal Spray
Dpressin Nasal Spray contains Desmopressin, which mimics the action of natural antidiuretic hormone (Vasopressin) by binding to V2 receptors in kidney collecting ducts. This increases water reabsorption and reduces urine volume, helping maintain proper fluid balance.
Dpressin Nasal Spray offers multiple therapeutic benefits:
- Effectively manages central Diabetes Insipidus by replacing missing Vasopressin.
- Reduces excessive nighttime urination (nocturia) in adults with deficient nocturnal ADH secretion.
- Controls bedwetting in children by decreasing nighttime urine production.
- Provides convenient intranasal administration for appropriate patients.
Proper fluid intake management is essential while using Dpressin to avoid water retention and Hyponatremia.
How to take Dpressin Nasal Spray
Dpressin Nasal Spray is a prescription medication that should be taken as per your doctor's instructions. Here are the general guidelines:
- Before first use, prime the pump by pressing down 4 times.
- Hold the bottle upright and insert the nozzle into the nostril. Press down firmly on the pump to deliver one spray while sniffing gently.
- Depending on the condition, adults typically require 1-2 sprays in each nostril. For children, dosage is determined by weight and medical condition. Do not exceed prescribed doses, as this may lead to water retention.
Strengths and substitutes
The strengths and substitutes available for Minirin spray are:
| $37.47 |
What are the side effects of Dpressin Nasal Spray
Dpressin Nasal Spray is generally well-tolerated when used correctly. However, it may cause side effects, including:
- Nasal irritation, congestion, or rhinitis
- Headache or mild dizziness
- Nausea or abdominal pain
- Hyponatremia (low blood sodium) with symptoms like headache, confusion
Most of these adverse effects are mild and transient. However, symptoms of Hyponatremia require immediate medical attention as this can be serious.
Safety Advice
Liver disease
People with moderate to severe liver problems should use Dpressin with caution. Lower starting doses with careful titration are recommended. Regular serum sodium level monitoring is essential, particularly during dose adjustment periods.
Kidney impairment
Patients with significant kidney dysfunction may have an altered response to Desmopressin and an increased risk of water retention and Hyponatremia. Dpressin should not be used in these patients.
Pregnant and breastfeeding women
Dpressin should be used during pregnancy only if needed. Limited data suggest no increased risk of birth defects, but benefits must outweigh potential risks. Small amounts might pass into breast milk, but effects on breastfed infants are unlikely at therapeutic doses. Consult your healthcare professional before using while pregnant or breastfeeding.
Avoid
Excessive fluid intake while using Dpressin increases the risk of water intoxication and Hyponatremia. Alcohol consumption should be avoided as it may enhance the antidiuretic effect. Certain medications like NSAIDs, SSRIs, and tricyclic antidepressants may increase the risk of Hyponatremia when used with Dpressin.
FAQs
How long does it take for Dpressin to work?
Dpressin Nasal Spray typically begins working within 15-30 minutes after administration. The antidiuretic effect usually lasts between 8 and 12 hours, depending on the individual response and dosage.
Can I use Dpressin for a long time?
Long-term use is possible under medical supervision with regular monitoring. Some patients with chronic conditions like central Diabetes Insipidus may require lifelong therapy with appropriate dose adjustments over time.
What happens if I use too much Dpressin?
Overdose can lead to water retention and Hyponatremia. Symptoms include headache, nausea, vomiting, confusion, drowsiness, decreased urine output, and, in severe cases, seizures or coma. Seek immediate medical help if a Dpressin overdose is suspected.
Can children use Dpressin Nasal Spray?
Yes, children can use Dpressin for certain conditions like central Diabetes Insipidus and primary nocturnal enuresis, but a pediatric specialist must carefully determine dosing. Close monitoring is essential, especially at treatment initiation.
What should I do if I forget a dose?
If you remember, within an hour or two, take the missed dose. If it's closer to your next scheduled dose, leave the missed Dpressin dose and continue with your regular schedule. Never double up to make up for missed doses. Always follow the advice of your doctor.