Enhertu 100mg Injection
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$5,220.91
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SKU
CMS8507
What is Enhertu 100 mg
Enhertu 100 mg delivers targeted therapy for HER2-positive cancers through advanced antibody-drug conjugate technology. The active ingredient Trastuzumab Deruxtecan combines precise tumor targeting with potent chemotherapy delivery.
This innovative approach minimizes damage to healthy cells while maximizing therapeutic impact. AstraZeneca manufactures this breakthrough oncology treatment.
The medication specifically targets HER2-expressing cancer cells throughout the body. It binds to HER2 receptors before releasing cytotoxic payload directly into malignant tissue.
Common treatment-related effects include fatigue, nausea, and temporary blood count changes. Regular monitoring helps manage these expected responses effectively. Proper handling requires specialized healthcare facility administration only.
Store vials in refrigerated conditions between 36-46°F until preparation. To maintain structural integrity, never shake or freeze the medication. Protect from light exposure during storage and transport.
Patients with a severe history of Interstitial Lung Disease require alternative treatment options. Those with active infections need medical clearance before therapy initiation. Healthcare teams monitor for potential Pneumonitis development during treatment cycles.
What are the benefits of Enhertu 100 mg
Enhertu 100 mg works through antibody-drug conjugate mechanisms targeting HER2-overexpressing tumors. Trastuzumab Deruxtecan delivers topoisomerase I inhibitors directly to cancer cells. This precision approach reduces systemic toxicity while maintaining therapeutic efficacy. The conjugate releases cytotoxic payload, specifically within the tumor microenvironment.
Key therapeutic advantages include:
- Superior progression-free survival in clinical trials
- Effective against HER2-low expressing tumors
- Reduced resistance compared to traditional chemotherapy
- Improved quality of life during treatment
The medication overcomes resistance mechanisms seen with previous HER2-targeted therapies. Clinical studies demonstrate significant tumor shrinkage in heavily pretreated patients.
Response rates exceed those of conventional chemotherapy combinations. The treatment offers hope for patients with limited therapeutic options.
It is crucial to note that treatment requires specialized oncology care and regular monitoring for optimal outcomes.
How to take Enhertu 100 mg
Enhertu injection is a prescription medication that should be taken as per your doctor's instructions. Here are the general guidelines:
- Receive Enhertu through intravenous infusion only.
- Administration occurs in specialized cancer treatment facilities. Treatment cycles typically repeat every three weeks.
- Do not attempt self-administration outside medical supervision.
Strengths and substitutes
There are no strengths and substitutes available for the Enhertu injection at Cheap Medicine Shop.
What are the side effects of Enhertu 100 mg
Enhertu 100 mg is generally manageable with proper medical supervision and supportive care. However, it may cause side effects, including:
- Fatigue
- Weakness
- Nausea
- Vomiting
- Decreased appetite
- Weight loss
- Low blood cell counts
These adverse effects resolve with treatment. However, severe ones typically require medical monitoring and may need supportive treatments during therapy.
Safety Advice
Liver disease
Patients with mild liver impairment can receive Enhertu with dose modifications and frequent monitoring. Those with moderate to severe hepatic dysfunction require careful assessment and potential dose reductions. Regular liver function testing ensures safe treatment continuation.
Kidney impairment
Mild to moderate kidney dysfunction does not typically require dose adjustments for Enhertu. Severe renal impairment patients need individualized dosing based on kidney function assessment. Regular monitoring helps prevent accumulation-related toxicity.
Pregnant and breastfeeding women
Enhertu is contraindicated during pregnancy due to severe fetal developmental risks and potential death. Women must use effective contraception during treatment and for 7 months after the final dose. Breastfeeding should be discontinued during therapy.
Avoid
Avoid live vaccines during treatment as immune system suppression increases infection risk. Do not take herbal supplements without an oncologist's approval. Avoid crowded places during low blood count periods to prevent serious infections.
FAQs
How long does Enhertu 100 mg infusion take?
Initial infusion typically takes 90 minutes, with careful monitoring for allergic reactions. Subsequent treatments may be shortened to 30 minutes if well-tolerated. Healthcare teams adjust infusion rates based on individual patient response and tolerance.
Can I work while receiving Enhertu 100 mg treatment?
Many patients continue working with schedule adjustments around treatment days. Fatigue levels vary among individuals and may require flexible arrangements. Discuss workplace accommodations with your healthcare team for optimal quality of life.
What blood tests are needed during Enhertu 100 mg therapy?
Complete blood counts monitor for risks of Neutropenia, Anemia, and Thrombocytopenia. Liver function tests track the potential development of hepatotoxicity. Pulmonary function assessment helps detect early signs of Interstitial Lung Disease that require immediate attention.
How should I manage nausea from Enhertu 100 mg?
Anti-nausea medications prescribed before infusion help effectively prevent treatment-related nausea. Small, frequent meals throughout the day minimize digestive discomfort. Ginger tea and bland foods often provide additional symptom relief.
What are the signs of serious side effects with Enhertu 100 mg?
Seek immediate medical attention for a persistent cough, shortness of breath, or chest pain, which may indicate potential lung complications. Fever, chills, or unusual bleeding may signal dangerous blood count drops requiring emergency intervention.