Fondared 7.5 mg injection delivers anticoagulation therapy through Fondaparinux sodium. This synthetic pentasaccharide belongs to the selective Factor Xa inhibitors class. Dr Reddy's Laboratories Ltd manufactures this blood thinner medication in GMP-compliant facilities.
The injection prevents dangerous blood clot formation in various clinical situations. Fondaparinux specifically targets Factor Xa in the coagulation cascade. This mechanism blocks thrombin generation without directly affecting platelet function, providing predictable anticoagulation effects.
Healthcare providers use this medication to prevent Deep Vein Thrombosis (DVT). Pulmonary Embolism treatment represents another critical indication. Hip and knee replacement surgeries require prophylactic anticoagulation coverage.
Fondare is also used in the treatment of acute coronary syndromes (certain types of heart attack and severe angina). It can be prescribed after abdominal surgery or periods of immobilization.
Bleeding risks represent the primary safety concern during treatment. Regular monitoring helps detect complications early. Kidney function affects drug elimination significantly.
Pre-filled syringes ensure accurate dosing and convenient administration. Healthcare professionals handle injection preparation and delivery. Treatment duration depends on specific clinical indications and patient response factors.
Fondared 7.5 mg injection provides selective Factor Xa inhibition for precise anticoagulation control. Fondaparinux offers predictable pharmacokinetics without routine monitoring requirements. The synthetic structure minimizes the risk of Heparin-induced Thrombocytopenia (drop in platelet count due to Heparin).
Key therapeutic advantages include:
Clinical studies demonstrate superior efficacy in orthopedic surgery prophylaxis. The medication provides consistent anticoagulation without unpredictable responses.
The treatment eliminates the need for frequent laboratory monitoring. Fixed dosing simplifies clinical management protocols. Rapid onset ensures immediate anticoagulation protection when needed most.
Fondared 7.5 mg injection is a prescription medication requiring a healthcare professional’s administration. These are the general guidelines:
The strengths and substitutes available for Fondared 7.5 at Cheap Medicine Shop are:
| Fondared 2.5mg Injection | $35.56/injection |
Fondared 7.5 mg injection is generally safe under proper medical supervision. Potential side effects include:
These effects typically resolve without intervention and rarely require treatment discontinuation. However, medical help is necessary for symptoms that persist or worsen.
Liver disease
Liver dysfunction minimally affects Fondaparinux elimination since kidneys handle primary clearance. However, severe liver disease may increase bleeding risks due to reduced clotting factor production. Regular monitoring helps ensure safe treatment continuation. Do not use it without a doctor's consultation.
Kidney impairment
Kidney function critically affects Fondaparinux clearance, requiring monitoring for creatinine clearance of 30-50 ml/min. Severe renal impairment contraindicates treatment due to drug accumulation risks. Regular monitoring prevents dangerous drug accumulation and bleeding complications. Consult a doctor before use.
Pregnant and breastfeeding women
Fondared 7.5 mg injection crosses the placenta minimally but should be used only if prescribed and safe. Limited breastfeeding data suggest minimal infant exposure through breast milk. However, consulting a doctor is vital.
Avoid
Avoid aspirin and other antiplatelet medications unless specifically prescribed. NSAIDs increase bleeding risks significantly. Herbal supplements like ginkgo and garlic may enhance anticoagulation effects dangerously.
Fondared contains synthetic Fondaparinux, which selectively inhibits Factor Xa without affecting Factor IIa. This provides more predictable anticoagulation compared to unfractionated Heparin. It also minimizes the risks of Heparin-induced Thrombocytopenia complications.
Routine coagulation monitoring is not necessary due to predictable pharmacokinetics. However, kidney function tests and platelet counts should be monitored regularly. Anti-Xa levels may be measured in special circumstances, like obesity or pregnancy.
Home administration is possible after proper training by healthcare professionals. Patients must demonstrate correct injection technique and understand bleeding precautions. Medical supervision remains necessary to monitor effectiveness and detect potential complications.
Contact a healthcare provider immediately for guidance on missed doses. Do not double-dose to compensate for missed injections. Timing adjustments may be necessary to maintain therapeutic anticoagulation levels safely.
Anticoagulation effects persist for approximately 24 hours after subcutaneous injection. Peak activity occurs 2-3 hours post-injection. Complete elimination takes several days in patients with normal kidney function and longer with impairment.