Gibtulio Met 12.5mg/500mg Tablet

What is Gibtulio Met 12.5 mg/500mg

Gibtulio Met 12.5 mg/500mg is a combination medicine that treats Type 2 Diabetes in adults. Its primary ingredients are Empagliflozin (12.5mg) and Metformin (500mg), combining an SGLT2 inhibitor with a biguanide antidiabetic agent. Lupin Ltd is the manufacturer of Gibtulio Met 12.5 mg/500mg.

This medication effectively controls blood glucose levels through dual mechanisms. Empagliflozin blocks glucose reabsorption in the kidneys, while Metformin reduces glucose production in the liver and improves Insulin sensitivity.

Common side effects include nausea, diarrhea, urinary tract infections, and genital infections. These tablets should be stored in a cool, dry place away from direct sunlight. People with severe kidney or liver problems should use this medication with caution.

Regular checking of kidney function and blood glucose levels is vital. To avoid complications, take this medication exactly as prescribed by your healthcare provider.

What are the benefits of Gibtulio Met 12.5 mg/500mg

Gibtulio Met 12.5 mg/500mg provides comprehensive blood sugar control through its dual-action mechanism. Empagliflozin increases glucose excretion through urine by inhibiting SGLT2 transporters in kidney tubules.

Metformin decreases hepatic glucose production and enhances peripheral glucose uptake by improving Insulin sensitivity in muscle tissues. This combination offers several key benefits for Diabetic patients. It provides superior glycemic control compared to single-agent therapy.

The medication helps reduce body weight due to glucose loss through urine excretion. It may also provide cardiovascular protection in patients with established heart disease. The combination reduces the risk of Hypoglycemia compared to Insulin or sulfonylurea treatments.

It is crucial to note that this medication requires adequate kidney function for safe and effective use.

How to take Gibtulio Met 12.5 mg/500mg

Gibtulio Met is a prescription medication that should be taken as per your doctor's instructions. Here are the general guidelines:

• Take the Gibtulio Met tablet once daily with food.
• Swallow the tablet whole with a full glass of water without crushing or chewing.
• Maintain consistent timing between doses. Take with food to lower the chances of gastrointestinal side effects.
• Do not exceed 1 tablet daily or adjust dosage without consulting your healthcare provider.

Strengths and substitutes

The strengths and substitutes available for Gibtulio Met 12.5/500 at Cheap Medicine Shop are:

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What are the side effects of Gibtulio Met 12.5 mg/500mg

Gibtulio Met is generally well-tolerated when used appropriately.

However, it may cause side effects, including:

• Nausea
• Vomiting
• Diarrhea
• Urinary Tract Infections (UTIs) and increased urination frequency
• Genital yeast infections, particularly in women
• Metallic taste in the mouth
• Abdominal discomfort

These adverse effects typically do not require immediate medical consultation and disappear as your body adjusts to the medication. Seek medical help for severe side effects.

Safety Advice

Liver disease

Patients with liver impairment should use Gibtulio Met 12.5 mg/500mg with extreme caution. Metformin is contraindicated in severe hepatic dysfunction due to the increased risk of Lactic Acidosis. Regular liver function tests are recommended. Dose adjustment may be necessary based on liver function status and clinical response.

Kidney impairment

Gibtulio Met 12.5 mg/500mg is contraindicated in patients with severe kidney disease. Both components require dose adjustments in moderate kidney impairment. Regular monitoring of kidney function through creatinine and eGFR measurements is essential for safe long-term use.

Pregnant and breastfeeding women

Gibtulio Met 12.5 mg/500mg should be avoided during pregnancy as safety data is limited. Insulin is preferred for managing Diabetes during pregnancy. The medication might pass into breast milk, so breastfeeding mothers should consult their medical provider before use. Alternative treatments may be recommended during lactation.

Avoid

Avoid excessive alcohol as it increases the risk of Lactic Acidosis with Metformin. Limit grapefruit juice intake as it may affect medication absorption. Avoid dehydration and maintain adequate fluid intake to prevent kidney complications. Do not take it with iodinated contrast agents without medical supervision due to the risk of kidney injury.