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Glynase-MF Tablet
What is Glynase MF
Glynase MF is an oral antidiabetic medication manufactured by USV Pvt Ltd. It combines two FDA-approved active ingredients: Glipizide (5 mg) and Metformin (500 mg). Glipizide belongs to the drug class of Sulfonylurea, and Metformin is a Biguanide. It manages Type 2 Diabetes Mellitus.
Glipizide prompts the pancreas to produce more insulin, while Metformin lowers the liver's glucose production and enhances the body's response to insulin. This combination regulates blood sugar levels and reduces the risk of Diabetes-related complications like nerve damage, kidney issues, and heart disease.
The most common side effect of Glynase MF is low blood sugar levels (Hypoglycemia). That is why it is essential to eat regular meals and carry a source of glucose, such as sugary food, which includes sugar candy, fruit juice, and so on, to prevent such a drop in blood sugar. One can also suffer from severe Hypoglycemia if the medication is used alongside antifungal drugs (such as Miconazole). Alcohol may cause fluctuations in blood sugar levels, which patients should avoid. Other significant interactions include liver and kidney disease.
Maintaining a healthier lifestyle is crucial for better Diabetes management in these patients. Following the doctor's instructions, incorporating a balanced diet and exercise helps better Diabetes control.
What are the benefits of taking Glynase MF
The benefits of this medication come from its combination of two effective antidiabetic agents: Glipizide and Metformin.
- Glipizide helps the pancreas to produce more insulin, whereas Metformin decreases glucose production in the liver and enhances the body's response to insulin, leading to improved blood sugar regulation.
- It helps manage and stabilize blood glucose levels when diet and exercise aren't enough, thereby reducing the chance of getting Diabetes-related complications like nerve damage, kidney issues, and heart disease.
- The combination can provide improved glycemic control compared to single-drug therapy and may help prevent sudden spikes in blood sugar after meals.
- When used as prescribed and combined with a healthy lifestyle, Glynase MF supports long-term Diabetes management, assisting patients to maintain a better quality of life.
How to take Glynase MF
It is a prescription-based antidiabetic medication that patients should take according to their doctor's instructions. Here are some general guidelines.
- Take the dose as prescribed by your doctor.
- It should be taken with food.
- Swallow the whole tablet with water. Do not crush or chew it.
- Take the tablet at a fixed time daily for better results.
Strengths and Substitutes
No strengths of Glynase MF are available at Cheap Medicine Shop. However, substitutes with the same salt are available.
| Glimet DS 5/500 Mg Tablet | $1/10 tablets |
What are the side effects of Glynase MF
Most side effects of this medication are mild and will subside in due time. However, if the symptoms continue or worsen, consult a doctor immediately.
- Low blood sugar level (Hypoglycemia)
- Nausea
- Diarrhea
- Dizziness
- Headache
Safety Advice
Liver disease
Patients with liver disease should take the medication with caution. It is not advised for those with severe liver impairment, as it may raise the risk of serious side effects like Lactic Acidosis, a condition linked to Metformin. Dose adjustments and regular monitoring may be required for patients with mild to moderate liver issues.
Kidney impairment
Patients with kidney impairment should use the medication with caution. The Metformin component can accumulate in the body if kidney function is reduced, increasing the risk of a rare but serious complication called Lactic Acidosis. Thus, Glynase MF is not recommended for patients with severe kidney dysfunction and may require dose adjustments and close monitoring in those with mild to moderate kidney problems.
Pregnancy and breastfeeding
The medication may not be safe during pregnancy, as limited data are available about whether it has any adverse effects on the fetus. Consult a doctor to weigh in on the potential benefits and the possible risks. Studies indicate that the active ingredients can be excreted into breast milk. While Metformin is generally considered safe, there is limited information on the effects of Glipizide during breastfeeding. It's crucial to consult a doctor for proper guidance and dose adjustments.
Avoid
Avoid taking the medication if you are allergic to Glipizide and Metformin. Alcohol can cause sudden changes in blood sugar levels, which patients should avoid. The changes in blood sugar levels may affect one's driving ability.
FAQs
Will Glynase MF cause me to lose weight?
Glynase MF is not primarily a weight loss medication. The Metformin component may help some people with mild weight loss by improving Insulin sensitivity and reducing appetite. However, Glipizide can cause weight gain in some people by increasing Insulin levels. The overall effect on your weight depends on your diet, exercise, and personal metabolism.
What is the duration of action of Glynase MF?
The duration of action of the Glynase-MF Tablet is influenced by its two active ingredients, Glipizide and Metformin. Glipizide typically works for about 12 to 24 hours, while Metformin's effects last around 6 to 12 hours in its immediate-release form.
What will happen if I overdose on Glynase MF?
Overdosing can lead to severe low blood sugar (Hypoglycemia), with symptoms such as dizziness, confusion, sweating, shaking, rapid heartbeat, hunger, headache, and even fainting. In some cases, overdose may also cause nausea, vomiting, stomach pain, muscle cramps, and a general feeling of unwellness.
How soon will I see improvement after starting Glynase MF?
You may see improvement in your blood sugar control within 1 to 2 days after starting Glynase MF. As the medication has a rapid onset of action, the effects can be observed within 30 minutes of taking a dose. However, the medication should be taken consistently, as prescribed, along with diet and exercise for fuller benefits.
How should I store Glynase MF?
Store the medication in a cool, dry place, away from direct sunlight and out of reach of children. Keep it in its original packaging until use, and dispose of unused tablets safely.