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Istamet XR Tablet
What is Istamet XR
Istamet XR is an extended-release combination tablet used to treat Type 2 Diabetes in adults. Its primary ingredients are Sitagliptin (100 mg) and Metformin (500 mg). Sitagliptin belongs to the DPP-4 inhibitors, while Metformin is a biguanide antidiabetic agent.
Sun Pharmaceuticals Industries Ltd is the leading manufacturer of this medication.
This combination medication effectively controls blood sugar levels. Sitagliptin works by increasing Insulin production when blood sugar is high, while Metformin reduces glucose production in the liver and improves Insulin sensitivity.
Common Istamet side effects include nausea, diarrhea, stomach upset, and headache. Most side effects are mild and temporary. Severe effects like Lactic Acidosis are rare but may occur and require immediate medical attention.
Store the medication at room temperature, away from moisture and heat. Keep it out of reach of children. Do not use expired tablets. Take this medication exactly as prescribed by your healthcare provider.
Always inform your doctor about other medications you are taking. Regular blood sugar monitoring is essential while using this medication.
What are the benefits of Istamet XR
This combination medication provides dual-action glucose control for Type 2 Diabetes management. Sitagliptin increases incretin hormones that stimulate Insulin release when blood glucose levels are elevated. It also reduces glucagon secretion from pancreatic alpha cells.
Metformin decreases hepatic glucose production and enhances peripheral glucose uptake. It improves Insulin sensitivity in muscle and fat tissues. The extended-release formulation provides consistent blood sugar control throughout the day.
Key benefits include improved glycemic control with reduced risk of Hypoglycemia. The combination offers better efficacy than the individual components alone. The extended-release formula allows once-daily dosing for better patient compliance.
It is crucial to note that this medication works best with a proper diet and routine exercise.
How to take Istamet XR
This medication is a prescription tablet that should be taken as per your doctor's instructions. Here are the general guidelines:
- Take once daily with your evening meal.
- Swallow the tablet whole with water. Do not crush or chew.
- Take with food at the same time each day for consistent blood levels.
- Do not exceed 1 Istamet tablet in 24 hours unless prescribed.
Strengths and substitutes
The strengths and substitutes available at Cheap Medicine Shop are:
| Istamet 50 Mg/1000 Mg Tablet | $15.00/10 tablets |
| Zita Met 50 Mg/500 Mg Tablet | $6.30/10 tablets |
What are the side effects of Istamet XR
This medication is generally well-tolerated. However, it may cause side effects, including:
- Nausea
- Vomiting
- Diarrhea
- Stomach discomfort
- Headache
- Dizziness
- Metallic taste in the mouth
They typically do not require medical consultation and disappear as your body adjusts. If they worsen, seek medical guidance immediately.
Safety Advice
Liver disease
Use with caution in people with liver impairment. Regular liver function monitoring is recommended. Based on liver function tests, a dose adjustment may be necessary. Discontinue if liver enzymes increase significantly. Always consult a doctor before use.
Kidney impairment
Contraindicated in severe kidney disease. Regular kidney function monitoring is essential. Dose reduction may be required in moderate kidney impairment. Stop medication if kidney function deteriorates significantly. Always consult a doctor before use.
Pregnant and breastfeeding women
Not recommended during pregnancy as safety is not established. Consult your doctor for alternative Diabetes management options. Avoid during breastfeeding as the medication may pass into breast milk.
Avoid
Avoid excessive alcohol as it increases the possibility of Lactic Acidosis. Avoid skipping meals to prevent Hypoglycemia episodes.
FAQs
Can I take this medication with other Diabetes medicines?
Consult your doctor before combining it with other antidiabetic medications. Drug interactions might increase the risk of Hypoglycemia. Your doctor will adjust doses accordingly for safe combination therapy. Avoid self-medication.
What should I do if I miss a dose?
Take the missed dose of Istamet tablets with your next meal. Do not take two doses together. Leave the missed one if it's almost time for your next scheduled dose. It is best to ask your doctor for specific instructions.
How long does it take to show results?
Blood sugar improvements typically occur within 2 to 4 weeks of regular use of Istamet. Maximum benefits are usually seen after 8 to 12 weeks of consistent treatment with a proper diet.
Can I drink alcohol while taking this medication?
Limit alcohol intake with Istamet as it may increase the risk of Lactic Acidosis. Occasional moderate drinking may be acceptable. Always consult your medical provider about alcohol consumption guidelines. If possible, avoid alcohol altogether during treatment.
What dietary changes should I make?
If using Istamet, follow a Diabetes-friendly diet with controlled carbohydrates. Include regular meals to prevent blood sugar fluctuations. Your dietitian can provide personalized meal-planning recommendations. It is vital to discuss this before starting medication.