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Janumet 50-1000 mg is an oral tablet prescribed to patients with type 2 Diabetes. Its two active ingredients, Sitagliptin, a DPP-4 Inhibitor, and Metformin, a Biguanide, work in tandem to lower blood sugar levels.
Manufactured by Merck Sharp & Dohme (MSD), Janumet 50-1000 mg is an oral tablet approved by the US Food and Drug Administration for treating type 2 Diabetes. This fixed-dose tablet can be taken alone or along with other diabetes medications. The dosage depends on the patient's conditions, medications, blood sugar levels, and lifestyle.
Take Janumet exactly as the doctor prescribed. Do not double-dose, overdose, or skip doses, as this may lead to lactic acidosis (a condition where blood becomes too acidic, causing weakness, breathing issues, and upset stomach). Common side effects include Diarrhea, upper respiratory tract infection, and headache. Avoid storing in hot and humid places, along with refrigerators, as it must be kept at room temperature.
There are no known significant food interactions. However, avoid alcohol consumption since this too can increase the risk of lactic acidosis. An important concern with Janumet is Hypoglycemia. Regarding drug interactions, insulin may increase the risk of low blood sugar when taken with Janumet, so dose adjustments may be required.
Janumet 50 - 1000 mg tablets offer several benefits for adults with type 2 Diabetes. They lower blood sugar levels by increasing insulin release after meals and reducing glucose production in the liver.
It is essential to consume Janumet as per the doctor's recommendations. Here is a general guideline:
The different strengths and substitutes of Janumet are available on cheapmedicineshop. It is advised to use substitutes only after consulting a healthcare provider to ensure effectiveness and safety. These are as follows:
| $6.80/ 10 Tablets | |
| $20.30/ 10 Tablets | |
| $20.30/ 10 Tablets | |
| $9.40/ 10 Tablets |
Like any medication, Janumet 50 mg 1000 mg may cause some side effects. Most side effects of Janumet are temporary and will subside once your body acclimates to the medication. The following are some of the side effects:
Liver disease
It is essential to let your doctor know if you have any liver diseases, as taking Janumet in such a state may lead to the risk of lactic acidosis or other undesired effects.
Kidney impairment
Take Janumet 50-1000 mg with caution in people with kidney dysfunction. Be transparent with your doctor and follow their instructions precisely. Get your kidneys checked regularly, as you may need to adjust your doses or discontinue if necessary.
Pregnant and breastfeeding women
It is essential to let your healthcare provider know if you are or have plans to become pregnant. A few studies do not recommend consuming Janumet 50 mg - 1000 mg during pregnancy or breastfeeding.
Avoid
Keeping track of your allergies is essential, especially if you are allergic to Metformin, Sitagliptin, or other tablet ingredients. Alcohol consumption should also be kept minimal due to the increased risk of lactic acidosis. Make sure to inform your doctor of all the medications you are on, or if you are planning any surgeries, to avoid any unknown complications.
If you miss a dose of Janumet 50-1000, take it as soon as you remember. However, if the next dose is near, skip the missed dose entirely. You must not double-dose. If you have any confusion or notice any symptoms, consult your doctors immediately.
Yes. Janumet 50-1000 mg may interact with herbal supplements, prescription drugs, OTC medicines, and alcohol. While no herbs are proven to interact directly, ginseng may enhance Sitagliptin’s effect, risking hypoglycemia. Always inform your doctor about all medicines and supplements to avoid unexpected interactions and ensure safe, effective treatment.
Yes, Metformin, one of the salts present in Janumet 50 mg - 1000 mg, can slightly lower LDL cholesterol and may also lower blood pressure. However, the effects are generally minor.
Yes. Janumet 50-1000 mg can affect specific lab test results. If you use this medication in the long term, your Vitamin B12 levels may get lower. Since doctors usually monitor kidney function and blood sugar control through regular blood and urine tests, tell your doctor you’re taking Janumet before doing any lab work.
No. On the contrary, it may result in slight weight loss for some people. A 24-week clinical trial published in Diabetes, Obesity and Metabolism showed that treatment with Sitagliptin combined with Metformin improved glycemic control and was weight-neutral or associated with slight weight loss.
