Levoflox 750 Mg IV Infusion 150 ml
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Levoflox 750 mg IV Infusion is a powerful broad-spectrum antibiotic for treating severe bacterial infections in adults requiring intravenous therapy. Its primary ingredient is Levofloxacin (750mg), a member of the fluoroquinolone class of antibiotics. Cipla Ltd, a renowned pharmaceutical manufacturer, produces this high-potency intravenous solution.
This medication effectively combats infections by inhibiting bacterial DNA gyrase and topoisomerase IV, preventing bacterial DNA replication. It's particularly effective against respiratory tract infections (Pneumonia, Bronchitis), Urinary Tract Infections (UTIs), skin infections, and certain gastrointestinal infections.
Common side effects of Levofloxacin include nausea, diarrhea, headache, and dizziness. Serious but rare effects include tendon rupture and nerve damage. Store Levoflox 750 mg away from direct light at room temperature.
The solution should appear clear. Discard it if it appears cloudy or contains particles. Medical supervision is required during administration to monitor for allergic reactions. Also, consult a doctor before using it if you have kidney or liver problems.
Levoflox 750 mg IV Infusion delivers a potent dose of Levofloxacin directly into the bloodstream, ensuring immediate bioavailability for critical infections. It targets and inhibits bacterial DNA gyrase and topoisomerase IV enzymes, preventing bacterial DNA replication and cell division. This ultimately kills the infectious bacteria.
The benefits include:
It is crucial to note that Levoflox 750 should only be used when oral antibiotics are unsuitable or for infections requiring immediate high-concentration treatment.
Levoflox 750 mg IV Infusion is a prescription medication that should be administered only under medical supervision. Here are the general guidelines:
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Levoflox 750 is generally well-tolerated when properly administered. However, it may cause side effects, including:
These adverse effects typically respond to symptomatic management. Serious side effects like severe allergic reactions, tendon rupture, or peripheral neuropathy require immediate medical attention.
Liver disease
Patients with liver impairment may require dosage adjustments as the liver partially metabolizes Levofloxacin. Regular liver function monitoring is recommended during treatment. In severe liver disease, the dosing interval may need to be extended to prevent drug accumulation.
Kidney impairment
Levoflox 750 mg IV requires significant dose reduction in patients with kidney impairment (CrCl <50 mL/min). Creatinine clearance should be calculated before starting therapy, and dosage or frequency should be adjusted accordingly. Regular kidney function monitoring is essential throughout treatment.
Pregnant and breastfeeding women
Levoflox is not recommended during pregnancy unless necessary, as fluoroquinolones may affect the fetus's developing cartilage. It should also be avoided during breastfeeding, as it is excreted in breast milk and may cause joint damage or other serious effects in nursing infants.
Avoid
Avoid concurrent administration with antacids containing aluminum, magnesium, or calcium, as these may significantly reduce Levofloxacin absorption. Maintain a 2-hour separation between infusion and these products. Also, avoid NSAIDs during treatment due to the increased risk of CNS stimulation and seizures.
The standard dosage is 750 mg (150 ml), administered intravenously once daily. The infusion should be given slowly over 90 minutes. The duration of treatment varies based on infection type and severity, typically 5 to 14 days, as determined by your healthcare provider.
Avoid antacids containing aluminum, magnesium, or calcium within 2 hours of administration. NSAIDs should be avoided due to seizure risk. Limit sun exposure as photosensitivity reactions may occur. Avoid strenuous physical activity that could stress tendons during treatment.
Levoflox IV Infusion delivers medication directly into the bloodstream, achieving higher blood levels immediately compared to oral forms. This makes it ideal for severe infections or patients who cannot take oral medications. It ensures 100% bioavailability and faster therapeutic action in critical infections.
Yes, Levofloxacin can rarely cause tendon inflammation or rupture, particularly of the Achilles tendon. The risk is higher in patients over 60 years of age, those taking corticosteroids, and those with kidney, heart, or lung transplants. Report any tendon pain or inflammation immediately to your healthcare provider.
Patients should be monitored for infusion site reactions, allergic responses, and vital signs during administration. Regular assessment of kidney and liver function is recommended. Patients should promptly report any unusual symptoms, such as tendon pain, numbness, tingling, mood changes, or heart rhythm disturbances.