Lispro 5 Mg Tablet
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$20.70
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SKU
CMS5723
What is Lispro 5 mg tablet
Lispro 5 mg is a therapeutic medication that contains Lisinopril (5 mg) as its active ingredient. It is primarily indicated for the management of essential Hypertension, the treatment of symptomatic congestive heart failure, and improving survival rates in individuals who have suffered an acute myocardial infarction.
Lisinopril is classified as an Angiotensin-converting Enzyme (ACE) inhibitor. It is manufactured by Johnlee Pharmaceuticals Pvt Ltd. The medication functions by preventing the conversion of angiotensin I to angiotensin II, reducing vasoconstriction and sodium retention, which helps lower blood pressure and alleviate strain on the heart.
Patients may experience side effects such as hypotension, dizziness, headache, and a characteristic dry cough; however, in rare instances, severe adverse reactions like angioedema may occur, necessitating immediate medical attention.
It is crucial to store Lispro 5 mg below 30°C in its original packaging, protected from light and moisture. Caution is advised for patients with Angioedema, Bilateral Renal Artery Stenosis, or Hyperkalemia. Regular monitoring of blood pressure, renal function, and electrolyte levels are recommended throughout the treatment duration to ensure optimal therapeutic outcomes and minimize potential complications.
What are the benefits of Lispro 5 mg tablet
Lispro 5 mg operates through a precise pharmacological mechanism that targets the Renin-Angiotensin-Aldosterone System (RAAS). Inhibiting ACE prevents the formation of angiotensin II, a potent vasoconstrictor. This action leads to decreased peripheral resistance, reduced afterload and preload on the heart, diminished aldosterone secretion, and decreased sodium and water retention.
The multifaceted benefits of Lispro 5 tablets include:
- Blood pressure normalization: Provides effective and sustained reduction in systolic and diastolic blood pressure.
- Cardiac function enhancement: Improves ejection fraction and reduces cardiac workload in heart failure patients.
- Renal protection: Decreases proteinuria and slows the progression of diabetic nephropathy.
- Vascular health improvement: Enhances endothelial function and arterial compliance.
- Mortality reduction: Significantly decreases cardiovascular mortality post-myocardial infarction.
It is essential to recognize that Lispro 5 mg may require 2-4 weeks of consistent administration to achieve maximum therapeutic efficacy.
How to take Lispro 5 mg tablet
Lispro 5 tablet is a prescription medication that should be taken per your doctor's instructions. Here are the general guidelines:
- Take a Lispro tablet once daily, typically in the morning. Maintain a consistent schedule for optimal blood levels.
- Swallow the tablet whole with a full glass of water. Do not crush, chew, or break it, which may alter its effectiveness.
- Do not exceed the prescribed dose, as overdosing may lead to unwanted side effects or complications.
If you miss a dose, take it as soon as you remember.
Strengths and substitutes
The strength and substitutes available for Lispro 5 mg at Cheap Medicine Shop are:
| $1.50 / 10 tablets | |
| $5.50 / 10 tablets |
What are the side effects of Lispro 5 mg tablet
Lispro 5 is generally well-tolerated by most patients. However, it may cause side effects, including:
- Persistent dry cough (most common)
- Orthostatic hypotension, especially after the initial dose
- Hyperkalemia (elevated potassium levels)
- Mild skin rash or pruritus
- Taste disturbances or decreased appetite
They are usually mild and temporary. However, seek immediate medical help if you experience severe dizziness, fainting, swelling of the face, lips, or tongue, or trouble breathing.
Safety Advice
Liver disease
Drug metabolism may be altered in people with hepatic impairment, but dosage adjustment is generally not required. However, monitoring of liver function tests is recommended during therapy initiation. In patients with severe hepatic disease, treatment should begin with a lower dose (2.5 mg) and be titrated cautiously under close medical supervision.
Kidney impairment
Lispro 5 elimination is primarily renal, necessitating careful dosage adjustment in people with impaired kidney function. For patients with creatinine clearance below 30 mL/min, the initial dose should be reduced to 2.5 mg daily. Regularly monitoring creatinine, blood urea nitrogen, and potassium levels is essential to prevent adverse effects.
Pregnant and breastfeeding women
Lispro is categorically contraindicated during pregnancy, particularly in the second and third trimesters, due to the risk of fetal developmental abnormalities, oligohydramnios, neonatal hypotension, skull hypoplasia, and even fetal death. Women who become pregnant while taking Lispro should discontinue treatment immediately and consult their healthcare provider. Limited data suggests Lisinopril passes into breast milk, so breastfeeding is not recommended during treatment.
Avoid
Avoid concurrent use of potassium-sparing diuretics, potassium supplements, or salt substitutes containing potassium, as they may precipitate dangerous hyperkalemia. Limit alcohol consumption as it may enhance hypotensive effects. NSAIDs can reduce the antihypertensive efficacy of Lispro and increase the risk of renal impairment. Grapefruit juice should be avoided as it may alter drug metabolism.
FAQs
How long does it take for Lispro 5 mg tablet to show effects?
Initial blood pressure reduction may occur within 1-3 hours after the first dose. However, maximum therapeutic benefits typically develop over 2-4 weeks of consistent daily administration. Regular blood pressure monitoring is essential during this initial period to evaluate the response and adjust the dosage if necessary.
How does Lispro 5 mg tablet help in managing high blood pressure?
Lispro 5 tablets blocks the enzyme that converts angiotensin I to angiotensin II, preventing vasoconstriction and aldosterone release. This dual action relaxes blood vessels, reduces fluid volume, and lowers resistance to blood flow, effectively decreasing blood pressure and reducing cardiovascular strain.
Can Lispro 5 mg be taken with other blood pressure medications?
Yes, Lispro 5 tablets can be combined with other antihypertensives, such as diuretics, calcium channel blockers, or beta-blockers, for enhanced blood pressure control. However, such combinations require careful monitoring by your healthcare provider to prevent excessive blood pressure reduction and adjust dosages accordingly.
What should I do if I experience a persistent cough while taking Lispro 5 mg?
A dry, persistent cough is a common side effect of ACE inhibitors like Lispro. If the cough becomes bothersome, consult your doctor, who may consider an alternative medication, such as an angiotensin receptor blocker (ARB), which provides similar benefits without typically causing a cough.
Why is it important to monitor kidney function while taking Lispro 5 mg?
Lispro 5 tablets can affect kidney function, particularly in patients with pre-existing renal impairment, diabetes, or those taking certain medications. Regular monitoring helps detect early changes in kidney function, allowing for timely dose adjustments or treatment modifications to prevent complications.