Lucrin Depot 3.25 mg is a hormonal therapy injection used to treat Prostate Cancer in men and Endometriosis in women. Its primary ingredient is Leuprorelin, a Gonadotropin-releasing hormone (GnRH) agonist.
Abbott Pharmaceuticals is the leading manufacturer of Lucrin Depot 3.25 mg.
Leuprorelin works by reducing the production of certain hormones in the body, specifically Testosterone in men and Estrogen in women. This helps slow or stop the growth of hormone-sensitive cancer cells in prostate cancer and reduces Endometriosis symptoms by creating a temporary, reversible Menopause-like state.
Common Leuprorelin side effects include hot flashes, decreased sexual desire, mood changes, and injection site reactions. In women, menstrual changes may occur. Long-term use may result in bone density loss. Store it in a cool, dry place away from direct sunlight. Refrigeration may be required before reconstitution; check package instructions.
It should be avoided in pregnancy and breastfeeding unless prescribed and is more beneficial than potential risks.
Lucrin Depot 3.25 mg Injection is a GnRH agonist that initially stimulates pituitary gonadotropin release, increasing sex hormone production. After continuous administration, it causes downregulation of GnRH receptors, leading to decreased LH and FSH production, ultimately reducing Testosterone or Estrogen to therapeutic levels.
The benefits of Lucrin Depot include:
It is crucial to note that treatment may cause symptoms to worsen initially (flare effect) during the first few weeks before improvement occurs.
Lucrin Depot is a prescription medication that should be taken as per your doctor's instructions. Here are the general guidelines:
The strengths and substitutes available for Lucrin Depot at Cheap Medicine Shop are:
| $322.27 / Injection |
Lucrin Depot 3.25 mg is generally well-tolerated. However, it may cause side effects, including:
These adverse effects typically subside as your body adjusts to the medicine. However, persistent or severe side effects should be reported to your healthcare provider.
Liver disease
People with liver disease may use Lucrin Depot with caution and prescription. No specific dose adjustment is generally required, but liver function should be periodically monitored during treatment. Consult a doctor if you have severe liver impairment.
Kidney impairment
Individuals with kidney impairment can use Lucrin Depot without specific dose adjustments. However, patients with severe kidney dysfunction should be monitored closely during treatment for any adverse effects. Always ask a doctor before use.
Pregnant and breastfeeding women
Lucrin Depot is contraindicated during pregnancy due to the possibility of fetal harm. Women should use effective non-hormonal contraception during treatment. Breastfeeding is not recommended during treatment with Lucrin Depot.
Avoid
Avoid hormone replacement therapy unless your doctor specifically prescribes it alongside Lucrin Depot. Consult your healthcare provider about all medicines and supplements you are taking.
Lucrin Depot typically has few significant drug interactions. However, it may interact with certain medications that affect hormone levels. Always inform your doctor about all medicines, supplements, and herbal products you're currently taking.
The standard dosage is 3.25 mg, administered as a monthly injection. Your doctor may adjust this based on your condition, treatment response, and side effects. Always follow your physician's recommendation.
Hormone levels may temporarily increase before decreasing. Most patients begin experiencing therapeutic benefits within 2-4 weeks of treatment. Full hormonal suppression typically occurs by the second month of therapy.
Some patients may experience weight changes during treatment. Weight gain can occur due to hormonal fluctuations and reduced metabolic rate. Regular exercise routines and a balanced diet may help manage this side effect.
Long-term use of Lucrin Depot may reduce bone mineral density, potentially increasing fracture risk. Your doctor may suggest calcium and vitamin D supplements, regular weight-bearing exercise, and bone density monitoring during treatment.