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Lupisit M 50mg/500mg Tablet
What is Lupisit M
Lupisit M 50mg/500mg Tablet is an antidiabetic medication manufactured by Lupin Ltd to treat Type 2 Diabetes Mellitus in adults. It contains two FDA-approved active ingredients: Sitagliptin (50 mg), a DPP-4 inhibitor, and Metformin (500 mg), a Biguanide. This combination is prescribed to help regulate blood sugar levels when diet, exercise, and single-drug therapy are insufficient.
Sitagliptin boosts incretin hormones, enhancing insulin secretion and reducing glucagon levels when blood sugar is elevated. Metformin increases insulin sensitivity, decreases liver glucose production, and slows glucose absorption from the intestines. Together, these actions help maintain blood sugar levels in these patients.
The most common side effects of this medication are diarrhea, headache, and vomiting. When used with other antidiabetic drugs, such as Insulin or Sulfonylureas, it may lead to low blood sugar (Hypoglycemia). Alcohol consumption can interfere with Lupisit M, causing unpredictable changes in blood glucose levels. Additionally, those with liver or kidney conditions should use it with caution due to potential interactions.
Patients should always inform their doctors of their medications to prevent complications. They should never skip out on the medication without a doctor's supervision. Maintaining a better lifestyle and monitoring blood glucose levels regularly is crucial for better Diabetes management.
What are the benefits of taking Lupisit M
The main benefits of taking Lupisit M 50mg/500mg Tablet are centered on effective blood sugar control for people with Type 2 Diabetes Mellitus.
- The combination of Sitagliptin and Metformin lowers high blood glucose levels and helps the body make use of insulin more efficiently.
- By maintaining stable blood sugar, Lupisit M helps one to avoid complications of Diabetes such as kidney damage (nephropathy), nerve problems (neuropathy), vision loss (retinopathy), diabetic foot ulcers, and delayed wound healing.
- It lowers the risk of major cardiovascular events like heart attack and stroke by keeping glucose levels within a healthy range.
- When used routinely with a healthy diet and regular exercise, Lupisit M supports better long-term Diabetes management and helps patients lead healthier, more active lives.
How to take Lupisit M
It is a prescription-based medication that should be taken per the doctor's recommendation. Here are some general guidelines for this medication.
- Take the dose as directed by the doctor.
- Swallow the tablet with water. Do not crush or chew it.
- Take it with food to prevent an upset stomach.
- Take it at a fixed time daily.
Strengths and Substitutes
No strengths of Lupsit M are available at Cheap Medicine Shop. However, substitutes with the same salt are available:
| Janumet 50 + 500 Mg Tablet | $6.70/10 tablets |
| Istamet 50Mg/500Mg Tablet | $15/10 tablets |
| Zita Met 50Mg/500Mg Tablet | $6.30/10 tablets |
What are the side effects of Lupisit M
The side effects of Lupisit M are:
- Headache
- Diarrhea
- Vomiting
- Stuffy or runny nose
- Indigestion
- Sore throat
They are temporary and will disappear as the body adjusts to the medication. However, if the symptoms continue or worsen, consult a doctor immediately.
Safety Advice
Liver disease
Lupisit M is usually not advised for patients with liver disease, as impaired liver function can impact how the drug is processed and eliminated from the body. It raises the risk of Lactic Acidosis, a rare but potentially life-threatening side effect linked to Metformin. It's crucial to consult a doctor for suitable alternatives or adjusted treatment.
Kidney Impairment
This medication is typically not advised for individuals with kidney impairment, as the kidneys are responsible for eliminating Metformin from the body. Impaired kidney may lead to a buildup of the drug, raising the risk of Lactic Acidosis, a serious condition linked to Metformin. You should consult a doctor for suitable treatment options.
Pregnancy and Breastfeeding
This medication is usually not advised during pregnancy because of limited data on its effects on the developing fetus. It's crucial to consult a doctor to weigh in on the possible risks and benefits. Likewise, breastfeeding mothers should seek medical advice before using the medication to make sure it is safe for both mother and child.
Avoid
Avoid taking the medication if you are allergic to Sitagliptin and Metformin. Alcohol can cause unexpected fluctuations in blood sugar levels and enhance the effect of Metformin, risking Lactic Acidosis. Driving may be affected if blood sugar is too high or too low.
FAQs
What if I miss a meal while taking Lupisit M?
Missing meals while taking Lupisit M can increase the risk of low blood sugar. You should always try to eat regular meals and carry a quick source of sugar in case you feel symptoms of Hypoglycemia (low blood sugar levels).
Can I take Lupisit M before surgery or medical imaging?
You should inform your doctor if you're scheduled for surgery or imaging, as Lupisit M (containing Metformin and Sitagliptin) may need to be paused before and after specific procedures, especially those involving anesthesia or contrast dyes, to lower the risk of Lactic Acidosis. Your doctor will guide you on when to stop and resume the medication.
What will happen if I overdose on Lupisit M?
Overdosing on Lupisit M 50mg/500mg Tablet is dangerous and can lead to serious, potentially life-threatening complications. The most significant risk is Lactic Acidosis, a rare but severe condition where lactic acid builds up in the blood.
Can Lupisit M 50 mg/500 mg Tablet cause vitamin B12 deficiency?
Yes, long-term use of Metformin (one of Lupisit M's active ingredients) may reduce the absorption of vitamin B12, potentially leading to deficiency. Your doctor may monitor your vitamin B12 levels during prolonged therapy.
How should I store Lupisit M 50 mg/500 mg Tablet?
You should store Lupisit M 50mg/500mg Tablet below 30°C in a cool, dry place, away from excessive light and moisture. To prevent accidental ingestion, keep the medication in its original container or packaging, tightly closed, out of reach of children and pets.