Lynparza 150mg Tablet
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CMS8508
What is Lynparza 150 mg
Lynparza 150 mg is an anticancer medication used primarily for the treatment and maintenance of certain advanced cancers, including ovarian, breast, pancreatic, and prostate cancers. The active ingredient, or salt name, is Olaparib. This drug is classified as a poly-ADP ribose polymerase (PARP) inhibitor and is manufactured by AstraZeneca.
Olaparib works by blocking the PARP enzymes, which repair damaged cell DNA. Cancer cells with BRCA mutations rely heavily on PARP for DNA repair, so inhibiting PARP causes these cancer cells to accumulate DNA damage and die. Lynparza is indicated for adult patients with specific types of advanced cancer, particularly those who have responded to prior platinum-based chemotherapy and have a BRCA mutation.
Common side effects include anemia, nausea, vomiting, and fatigue. Rifampicin, Carbamazepine, Phenytoin, and St. John's Wort can decrease Olaparib levels, potentially reducing its effectiveness. Avoid consuming grapefruit juice and Seville orange, as it can raise the blood levels of Olaparib and the risk and/or severity of side effects. Other significant interactions include kidney and liver disease.
Always inform your doctor and pharmacist about all prescription, over-the-counter, and herbal medications or supplements you are taking to lower the risk of harmful interactions.
What are the benefits of taking Lynparza 150 mg
The benefits of Lynparza 150 mg are:
- Lynparza helps people with certain advanced cancers (like ovarian, breast, pancreatic, or prostate cancers with BRCA gene changes) live longer without their cancer growing or spreading.
- It attacks cancer cells with trouble fixing their DNA, mostly leaving normal cells alone.
- Unlike many cancer treatments that require intravenous administration, Lynparza is taken orally as a tablet, making it more convenient for patients to use at home.
Thus, Lynparza 150 mg helps control cancer longer, targets cancer cells specifically, is easy to take, and can be used after other treatments.
How to take Lynparza 150 mg
Patients should take this prescription-based medication per the doctor's instructions. Here are some general guidelines.
- Take two tablets twice a day, with or without food.
- Swallow the whole tablet with water. Do not crush or chew it.
- Consult a doctor for any possible dose adjustments.
- Do not double up the dosage.
Strengths and Substitutes
The strengths and substitutes for Lynparza 150 mg available at Cheap Medicine Shop are:
| Lynparza 50 Mg Capsule | $193.50/10 tablets |
| Lynparza 100 mg Tablet | $1523.30/10 tablets |
What are the side effects of Lynparza 150 mg
The side effects of Lynparza 150 mg are:
- Anemia
- Nausea
- Vomiting
- Fatigue
- Weight loss
- Cough
They are temporary and will disappear as the body adjusts to the medication. However, if the symptoms continue or worsen, consult a doctor immediately.
Safety Advice
Liver disease
It is typically safe for patients with mild liver disease to use the medication, with no possible dosage adjustments. However, as a precautionary measure, consult a doctor before taking it. Caution is advised for patients with moderate to severe liver disease.
Kidney impairment
Lynparza 150 mg is generally safe for patients with kidney impairment. However, as a precautionary measure, consult a healthcare professional before use. Caution is advised for patients with moderate to severe kidney impairment.
Pregnancy and breastfeeding
The medication is not generally advised for use during pregnancy as there can be potential risks to the baby. Consult a doctor for appropriate treatment. It's unclear how much Olaparib passes into breast milk and whether it could impact a nursing infant. Always consult a doctor for guidance and treatment.
Avoid
Avoid the medication if you are allergic to Olaparib. Also, avoid consuming grapefruit juice and Seville oranges, as they can raise the blood levels of Olaparib and the risk and/or severity of side effects.
FAQs
What should I tell my doctor before starting Lynparza 150 mg?
Tell your doctor about all your medical conditions and all medicines, vitamins, and supplements you take. Lynparza can interact with many drugs, and informing your physician about all your medications will help prevent any complications.
How will my doctor monitor me during treatment?
Your doctor will check your blood cell count and monitor your liver and kidney function before and during treatment. Before you start treatment, and then monthly during the first year, your doctor will order complete blood counts to check for changes in your blood cells, such as anemia, low white blood cells, or low platelets. These tests help detect any hematological toxicity early.
How is Lynparza different from chemotherapy?
Lynparza is a targeted therapy that blocks the PARP protein, which helps cancer cells with specific DNA repair problems die. Chemotherapy works by killing rapidly dividing cells, including both cancer and some healthy cells.
How should Lynparza 150 mg be stored?
Store Lynparza 150 mg tablets at a temperature between 20°C and 25°C (68°F and 77°F) in their original container to protect them from moisture. Brief exposure to temperatures between 15°C to 30°C (59°F and 86°F) is acceptable.
Should I be concerned about infections while taking Lynparza 150 mg?
Yes, Lynparza can lower your ability to fight infections. Avoid close contact with sick people, and contact your physician if you develop a fever, chills, sore throat, or other symptoms of infection.