Mofloren D 5 ml is a prescription-based ophthalmic solution used to treat bacterial infections and post-surgical eye inflammation. It contains two FDA-approved active ingredients, Moxifloxacin Hydrochloride (0.5% w/v) and Dexamethasone Sodium (0.1% w/v). Moxifloxacin belongs to the Fluoroquinolone antibiotic class, while Dexamethasone is a Corticosteroid. Indoco Remedies Ltd. manufactures Moxifloxacin and Dexamethasone ophthalmic solution in its GMP-compliant facilities.
Moxifloxacin's mechanism of action involves inhibiting two bacterial enzymes, topoisomerase IV and DNA gyrase, which are crucial for DNA replication. This action leads to bacterial cell death. On the other hand, Dexamethasone suppresses cytokines and prostaglandins, which are inflammation-promoting chemicals, thereby reducing swelling, pain, and redness.
As an ophthalmic combination therapy, the primary uses of Mofloren D 5 ml include the treatment of Bacterial Conjunctivitis and the control or prevention of inflammation, itching, and redness after an eye procedure or due to trauma.
Some users can experience side effects after using Mofloren D 5 ml. They include blurred vision, redness or dryness of the eyes, and a burning sensation. These are usually mild and temporary; however, see a doctor if they last for a long time.
Take Mofloren D 5 ml exactly as prescribed for safe use. Generally, 1 to 2 drops are instilled in the affected eye 3-4 times a day for bacterial infection and 4 times a day for 15 days for post-surgery use.
In case of an overdose, rinsing the eyes with clean water will remove excessive solution. In contrast, for a missed dose, instill it when remembered and skip it when it's close to the next dose.
Precautions include informing your doctor of any eye injuries, Glaucoma, or viral and fungal eye infections, and avoiding use with contact lenses. Moreover, Mofloren is known to interact with immunosuppressants and other steroid eye drops, increasing the risk of side effects. Therefore, avoid combining them with this eye drop.
Store the eye drop below 25°C and keep it away from direct sunlight and moisture. Avoid freezing the medication and keep the bottle cap tightly closed. Keep out of reach of pets and children, and discard the bottle by the expiry date or 4 weeks after opening it.
This ophthalmic solution provides targeted relief for inflammation and bacterial eye infections. Primary benefits of Mofloren D 5 ml are as follows:
Mofloren D 5 ml is intended for external eye use only. Consult your doctor first and use only with a prescription. General guidelines include:
Currently, only substitutes are available for Mofloren D 5 ml at Cheap Medicine Shop. Ensure consulting a doctor before using the substitutes:
| Moxiblu D 10 ml | $3.70/bottle |
| Mosi D 5 ml | $3.70/bottle |
| Myticom 5 ml | $3.70/bottle |
Like any medication, Mofloren D 5 ml can trigger adverse effects in some users. Note that these effects are mild, temporary, and need medical treatment only when they subside for longer. Common side effects are listed below:
Liver disease
Mofloren D is used topically in the eyes, resulting in low systemic absorption. Therefore, no reported liver interactions. But, for severe liver diseases and prolonged Mofloren use, be cautious and consult a doctor first.
Kidney impairment
Dose adjustments are usually not required in individuals with kidney impairment since the medication acts locally. However, consult a doctor for extended use.
Pregnant and breastfeeding women
Safety data for pregnant and breastfeeding women is limited. Therefore, use it strictly when prescribed by a doctor.
Avoid
Avoid Mofloren D 5 ml if allergic to Dexametasone and Moxifloxacin. Remove contact lenses before use, and avoid combining the medication with other ophthalmic steroid or antibiotic solutions. Also, avoid extended use without medical supervision since it has a steroid that can increase the risk of Glaucoma and secondary eye infections.
Mofloren D eye drops, containing Dexamethasone and Moxifloxacin as active ingredients, are primarily used to treat Bacterial Conjunctivitis and to reduce inflammation after eye procedures such as cataract surgery. It inhibits bacterial growth and reduces inflammatory responses such as swelling, redness, and irritation.
No, Mofloren is not available over the counter and requires a valid prescription from the doctor, since it contains a steroid and an antibiotic. Therefore, it requires medical supervision to reduce the risk of Glaucoma, prevent misuse and antibiotic resistance.
Mofloren D 5 ml has minimal interaction due to low systemic absorption from eye use. However, it can interact with other eye medications belonging to the class of Non-steroidal Anti-Inflammatory Drugs (NSAIDs), increasing the risk of corneal thinning and delaying recovery. Therefore, wait at least 5-10 minutes between using multiple eye drops.
Moxifloxacin kills a broad spectrum of bacteria, including Gram-positive bacteria such as Streptococcus pneumoniae, Streptococcus pyogenes, Staphylococcus aureus, and Enterococcus spp. It also kills Gram-negative bacteria, including Klebsiella, Haemophilus influenzae, and Pseudomonas aeruginosa, as well as anaerobes such as Clostridium spp. and Bacteroides fragilis, and others, such as Chlamydia trachomatis.
You should use Mofloren eye drops for the prescribed duration, usually 7 to 15 days, even if symptoms improve earlier. It is suggested not to exceed 15 days with medical review to avoid risks associated with steroids.
If you use steroid eye drops for too long, it can increase the risk of elevated eye pressure and cataract formation, and can delay healing. Moreover, it can thin the cornea and make the eyes more prone to infections.
If you don't refrigerate eye drops, such as Mofloren, they're fine at room temperature (15°C to 25°C), as they are formulated to be stored within this range. Temperatures above this range can degrade its active ingredients and reduce its effectiveness.