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Pruwel 1 is a prescription medication used for managing persistent idiopathic constipation in adults when other laxatives (substances that promote bowel movements) fail. The active salt is Prucalopride (1 mg), an FDA-approved selective 5-hydroxytryptamine type 4 (5-HT4) receptor agonist manufactured by Intas Pharmaceuticals Ltd. in a GMP-compliant facility.
Prucalopride, also known as a prokinetic laxative (substances that promote bowel movement) or serotonergic neuroenteric modulator, works by activating serotonin receptors in the gut wall. This causes natural muscle contractions that drive waste through the colon.
The normal dose is 1 mg once daily; however, people over 65 or with kidney problems are often prescribed a starting dose of 1 mg. If you miss a dosage, take it as soon as possible, but avoid it if your next dose is approaching. Acquire emergency medical help if you suspect an overdose with symptoms including extreme diarrhea or headache.
Frequent adverse effects include headaches, nausea, and stomach discomfort. Get emergency medical help if you are experiencing irregular heartbeat or mood swings. Avoid taking the medicine if you have intestinal blockage or Crohn's disease (chronic inflammatory bowel disease) or are taking other medicines like Verapamil.
Keep this serotonin receptor agonist at room temperature away from direct heat and moisture.
Prucalopride in Pruwel promotes bowel contractions by activating serotonin receptors. This encourages regular and spontaneous bowel motions. The benefits include:
Pruvict provides long-term comfort from chronic constipation by addressing the underlying motility issue rather than merely the symptoms, enhancing everyday comfort and well-being.
Follow your doctor's instructions to get the most out of this bowel movement stimulant. However, a few common usage instructions are:
At present, there are no other strengths available for this chronic constipation treatment at Cheap Medicine Shop. If you need a different dosage, consult with your doctor to select the safest and most suitable alternative from the other available options on our online pharmacy.
Some commonly recommended substitutes for Prusent include:
| Voveran SR 75 mg | $3.00/10 pills |
| Pantop 40 mg | $4.40/10 pills |
When starting this functional constipation therapy, you might notice temporary and mild side effects such as:
These side effects generally fade away without any medical aid as your body starts adjusting to the medication. Contact your doctor if these symptoms become bothersome or do not go away.
Liver Disease
Since this gut motility medicine is metabolized by the liver, decreased liver function can affect the medicine's metabolism and increase the likelihood of adverse effects. To ensure both safety and medicinal benefits, doctors can modify the dosage or recommend alternative treatments.
Kidney Impairment
Prucalopride in this colon movement support medicine can decrease kidney function. It can accumulate in people with kidney disease, raising the risk of adverse effects. Therefore, individuals with kidney illness should avoid it unless particularly prescribed by their doctor.
Pregnant and Breastfeeding women
Since the effects of these Prucalopride tablet tablets during pregnancy and breastfeeding have not been thoroughly investigated or established, it is advisable to avoid taking them without a doctor's guidance.
Avoid
Avoid drinking alcohol with this digestive system medicine, as it can strain the digestive system and increase the risk of adverse reactions.
Pruwel can start stimulating bowel movement within a few hours, but consistent improvement is usually noticed within 1–3 days of daily use. This duration might vary depending on individual bowel activity and severity of constipation.
Pruwel tablets are recommended for adults suffering from chronic idiopathic constipation, especially those who have not responded well to fiber supplements, stool softeners, or traditional laxatives.
Yes, Pruwel is generally considered safe for long-term use when taken as prescribed. However, regular medical follow-up is recommended to monitor effectiveness, side effects, and overall bowel health.
You must get immediate medical help if you experience chest pain, irregular heartbeat, severe abdominal pain, fainting, or symptoms of an allergic reaction such as swelling, rash, or difficulty breathing.
No, Pruwel generally has a low risk of affecting the heart because prucalopride is highly selective for 5-HT4 receptors. However, patients with existing heart conditions should use it cautiously under the guidance of a medical professional.
No, Pruwel tablets are generally not recommended for children and adolescents under 18 years of age, as safety and efficacy of the medication in this age group have not been well established.
No, Pruwel is usually taken alone and does not require additional laxatives. Combining it with other laxatives may cause excessive bowel stimulation or diarrhea, so it should only be done if specifically advised by your doctor.
