Quel SR 300 Tablet
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$45.23
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CMS4075
What is Quel SR 300 tablet
Quel SR 300 tablet is an extended-release antipsychotic medication containing Quetiapine (300mg) as its active ingredient, which belongs to the atypical antipsychotic. This sustained-release formulation is primarily prescribed for the management of Schizophrenia and bipolar disorder and as an adjunct treatment (in addition to primary therapy) for major depressive disorder in adults.
Manufactured by Ipca Laboratories Ltd, a leading pharmaceutical company recognized for its psychiatric medications, Quel SR 300 delivers consistent therapeutic effects over an extended period. The sustained-release technology allows for once-daily dosing, improving medication adherence and providing stable blood levels throughout the day.
Quetiapine modulates multiple neurotransmitter systems in the brain, particularly blocking dopamine and serotonin receptors. This mechanism helps manage symptoms such as hallucinations, delusions, disorganized thinking, mood swings, and severe depression.
Common Quetiapine side effects include drowsiness, dizziness, dry mouth, constipation, and weight gain. More serious and rare side effects are changes in blood sugar or cholesterol levels or abnormal movements.
Quel tablets should be stored at room temperature and protected from light and moisture. Patients should know that this medication requires proper titration when starting or discontinuing treatment, and abrupt discontinuation should be avoided. Healthcare providers must regularly monitor metabolic parameters during treatment.
What are the benefits of Quel SR 300 tablet
Quel SR 300 delivers multiple therapeutic benefits through its complex pharmacological profile. Quetiapine is an antagonist at multiple neurotransmitter receptors, including dopamine D1 and D2, serotonin 5-HT1A and 5-HT2, histamine H1, and adrenergic alpha1 and alpha2 receptors. This multifaceted action contributes to its efficacy across several psychiatric conditions.
The medication offers distinct benefits for different psychiatric conditions:
- For Schizophrenia: Reduces positive symptoms (hallucinations, delusions) and negative symptoms (social withdrawal, lack of motivation).
- For Bipolar Disorder: Stabilizes mood swings, prevents manic episodes, and reduces depressive symptoms.
- For significant depression: Enhances the effects of antidepressants when used as an adjunctive treatment.
- For anxiety disorders: Provides relief from anxiety symptoms associated with primary psychiatric conditions.
The sustained-release formulation ensures consistent blood levels over 24 hours, reducing dosing frequency and minimizing peak-related side effects. This improves tolerability and treatment adherence, critical factors for long-term management of chronic psychiatric conditions.
It is crucial to note that Quel SR requires careful monitoring for metabolic side effects, including weight gain, blood glucose changes, and lipid abnormalities.
How to take Quel SR 300 tablet
Quel SR 300 is a prescription medication that should be taken per your doctor's instructions. Here are the general guidelines:
- Take Quel SR once daily, preferably in the evening.
- Swallow the tablet with water. Do not crush or break the tablet.
- It can be taken with or without food, but food may reduce the chances of stomach upset.
- Do not exceed the prescribed dosage or abruptly discontinue the medication.
Strengths and substitutes
The strength and substitutes available for Quel SR are:
| $10.6 / 10 tablets | |
| $18.7 / 10 tablets | |
| $15.3 / 10 tablets |
What are the side effects of Quel SR 300 tablet
Quel SR is generally effective when properly prescribed. However, it may cause side effects, including:
- Drowsiness, sedation, and dizziness
- Dry mouth, constipation, and indigestion
- Weight gain and increased appetite
- Elevated blood sugar and cholesterol levels
- Fatigue and mild hypotension (low blood pressure)
These adverse effects often improve as your body adjusts to the medication. However, if they persist or worsen, consult your healthcare provider promptly.
Safety Advice
Liver disease
Patients with liver impairment require dose adjustment. For those with mild to moderate liver issues, starting with a lower dose (typically 50mg daily) is recommended with gradual titration. Those with severe liver disease should use Quel SR with extreme caution, requiring substantial dose reduction and close monitoring of liver function.
Kidney impairment
No specific dose adjustment is required for mild to moderate kidney impairment. However, those with severe kidney disease should be monitored closely during treatment initiation and dose titration. Regular kidney function tests may be advised during long-term treatment.
Pregnant and breastfeeding women
Quel SR should be used during pregnancy only if the benefits justify the risks to the fetus. Limited data suggests possible withdrawal symptoms in newborns exposed to Quetiapine during the third trimester. Breastfeeding while taking Quel SR is not recommended as the drug passes into breast milk and may affect the nursing infant. Consult a doctor for safety.
Avoid
Alcohol should be strictly avoided while taking Quel SR as it may enhance sedative effects and increase the risk of liver damage. Grapefruit juice may increase Quetiapine blood levels, potentially worsening side effects. Avoid medicines that depress the central nervous system without medical supervision, as they may cause excessive sedation.
FAQs
How should Quel SR 300 Tablet be taken for best results?
Take Quel SR once daily in the evening or at bedtime. Swallow the tablet with water. Do not crush or chew it. This timing helps minimize daytime drowsiness while ensuring consistent blood levels throughout treatment.
How long does it take for Quel SR 300 to show therapeutic effects?
Some effects like sedation and anxiety reduction may be noticed within days, but full therapeutic benefits for Schizophrenia or Bipolar Disorder typically take 2-4 weeks to develop. Maintain regular dosing and follow-up with your doctor during this initial period.
Can I stop taking Quel SR 300 if I feel better?
Never stop taking Quel SR abruptly or without medical supervision. Sudden discontinuation may cause withdrawal symptoms or symptom relapse. Your doctor will help create a gradual tapering schedule when discontinuation is appropriate.
Does Quel SR 300 cause weight gain?
Weight gain is a common side effect of Quel SR, typically occurring within the first few months of treatment. Regular weight monitoring, implementing dietary changes, and incorporating physical activity can help manage this side effect.
Will Quel SR 300 affect my ability to drive or operate machinery?
Quel SR may cause drowsiness, dizziness, and blurred vision, particularly during the initial treatment. Avoid driving or activities that require attention, like operating hazardous machinery, until you know how the medicine affects you, typically for at least several days after starting or changing doses.