Rabeloc 40 Tablet
What is Rabeloc 40 mg tablet
Rabeloc 40 mg is primarily used to treat acid-related disorders in adults, such as Gastroesophageal Reflux Disease (GERD), Peptic Ulcers, and Zollinger-Ellison Syndrome. It is a potent proton pump inhibitor (PPI) containing 40mg of Rabeprazole sodium as its active ingredient.
Cadila Pharmaceuticals Ltd, a leading pharmaceutical manufacturer, markets Rabeloc 40 mg in India and various international markets. The medication dramatically reduces stomach acid production by blocking the hydrogen-potassium adenosine triphosphatase enzyme system (also called the proton pump) in the gastric parietal cells.
Common Rabeprazole side effects may include headache, nausea, stomach pain, and diarrhea, which are generally mild and transient. Rabeloc 40 tablets should be stored below 25°C in a dry place, protected from light and moisture. It should be taken as prescribed, typically once daily before a meal. The duration of treatment depends on the condition being treated.
What are the benefits of Rabeloc 40 mg tablet
Rabeloc 40 mg functions by irreversibly binding to and inhibiting the hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase) enzyme system on the surface of gastric parietal cells. This effectively suppresses gastric acid secretion regardless of the stimulus, providing fast and long-lasting relief from acid-related symptoms and allowing damaged tissues to heal.
The medication offers several therapeutic benefits:
- Effective healing of erosive esophagitis and relief from GERD symptoms.
- Treats and prevents gastric and duodenal ulcers.
- Management of hypersecretory conditions like Zollinger-Ellison syndrome.
- As combination therapy for Helicobacter pylori eradication.
- Protection against NSAID-induced gastroduodenal damage.
It is crucial to note that Rabeloc 40 provides symptomatic relief but does not address underlying causes of acid reflux, such as diet, lifestyle factors, or hiatal hernia.
How to take Rabeloc 40 mg tablet
Rabeloc 40 mg is a prescription medication that should be taken as per your doctor's instructions. Here are the general guidelines:
- Take Rabeloc 40 once daily, preferably in the morning, 30 minutes before breakfast. For best results, take the medication consistently at the same time each day.
- Swallow the tablet whole with a full glass of water; do not crush, chew, or break it.
- For best results, take it on an empty stomach before a meal.
- Do not exceed the prescribed Rabeprazole dosage unless specifically directed by your healthcare provider.
Strengths and substitutes
The strengths and substitutes available for Rabeloc are:
$6.50 / 10 tablets | |
$4.10 / 10 tablets |
What are the side effects of Rabeloc 40 mg tablet
Rabeloc is generally well-tolerated when used as directed. However, it may cause side effects, including:
- Headache and dizziness
- Nausea, abdominal pain, or diarrhea
- Flatulence and constipation
- Rash or itching (uncommon)
- Elevated liver enzymes (rare)
These adverse effects are usually mild. However, consult your doctor if you experience severe or persistent side effects, particularly if you develop signs of an allergic reaction.
Safety Advice
Liver disease
Patients with severe liver impairment should use Rabeloc 40 with caution. No dosage adjustment is typically required for mild to moderate liver dysfunction. Still, those with severe hepatic impairment should be monitored closely and may require dose reduction based on individual response.
Kidney impairment
No dosage adjustment is necessary for people with renal impairment. Rabeprazole is extensively metabolized in the liver, with minimal renal excretion of the parent compound. However, regular monitoring and consultation are still recommended for patients with severe kidney dysfunction.
Pregnant and breastfeeding women
Rabeloc should be used during pregnancy only if needed and when potential benefits outweigh possible risks. Limited data is available regarding the safety of Rabeprazole during pregnancy. It is not known whether it passes into breast milk, so caution is advised when administering it to nursing mothers. Consider the drug's importance to the mother when deciding whether to discontinue breastfeeding or the medication.
Avoid
Avoid alcohol consumption while taking Rabeloc 40, as it can increase stomach acid production and reduce the medication's efficacy. Certain medications, like Atazanavir and Nelfinavir, may have reduced absorption when taken with Rabeloc due to decreased stomach acidity. Inform your doctor about all medicines you take to prevent potential interactions.
FAQs
Can Rabeloc 40 Tablet be used for nausea and vomiting?
Rabeloc is not specifically indicated for nausea and vomiting unless these symptoms are related to acid reflux or Peptic Ulcer disease. While it may indirectly help by reducing acid-related discomfort, it's not a primary treatment for general nausea and vomiting.
How long should Rabeloc 40 Tablet be taken for stomach discomfort relief?
For Gastroesophageal Reflux Disease (GERD) symptoms, Rabeloc 40 mg typically provides relief within 2-3 days, with optimal results in 1-2 weeks. Treatment duration varies: 4-8 weeks for ulcers, 4-12 weeks for GERD, and possibly longer for maintenance therapy. Always follow your doctor's recommendations.
Can Rabeloc 40 mg be taken on an empty stomach?
Yes, Rabeloc is most effective when taken on an empty stomach, ideally 30 minutes before breakfast. This timing maximizes absorption and effectiveness by allowing the medication to reach peak plasma concentrations when acid production is highest.
Will long-term use of Rabeloc 40 mg cause vitamin deficiencies?
Prolonged use (typically over one year) may reduce vitamin B12, magnesium, and calcium absorption due to decreased stomach acid. Patients on long-term therapy should consider regular monitoring of these nutrients and discuss supplementation with their healthcare provider if necessary.
Can I take antacids along with Rabeloc 40 mg?
Occasional use of antacids with Rabeloc 40 mg is generally safe. However, separate administration by at least 2 hours to prevent interference with absorption. For persistent symptoms requiring regular antacid use alongside Rabeloc 40, consult your doctor for possible dosage adjustments.