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Siaglide-M OD 100/1000 Tablet PR
What is Siaglide M OD
Siaglide M OD is a combination medicine used to manage Type 2 Diabetes Mellitus in adults. It is manufactured by Abbott Healthcare Pvt Ltd. and contains two FDA-approved ingredients: Sitagliptin (100 mg), a DPP-4 inhibitor, and Metformin (1000 mg), a Biguanide.
Sitagliptin boosts incretin hormone levels, promoting insulin release and lowering glucagon levels when blood sugar is elevated. Metformin enhances insulin sensitivity, decreases the liver's glucose production, and slows down glucose absorption in the intestines. These mechanisms help regulate blood sugar levels effectively.
Common side effects include diarrhea, headache, and vomiting. The risk of Hypoglycemia increases when this medication is combined with other antidiabetic drugs like Insulin or Sulfonylureas. Alcohol should be avoided, as it may cause unpredictable changes in blood sugar. Patients with liver and/or kidney issues should use this medication cautiously due to possible complications.
Store the tablet in its original packaging at room temperature (below 30 °C) and protect it from moisture. Never stop taking the medication without consulting a doctor, as this may lead to a sudden rise in blood sugar levels. Monitoring blood sugar regularly is essential for proper dosage adjustments and effective diabetes management.
How to take Siaglide M OD
It is a prescription-based medication that should be taken per the doctor's recommendation. Here are some general guidelines for this medication.
- Take the dose as directed by the doctor.
- Swallow the tablet with water. Do not crush or chew it.
- Take it with food to prevent an upset stomach.
- Take it at a fixed time daily.
Strengths and Substitutes
No strengths of Siaglide M OD are available at the Cheap Medicine Shop. However, substitutes with the same salts are available:
| Janumet 50 + 500 Mg Tablet | $6.70/10 tablets |
| Istamet 50Mg/500Mg Tablet | $15/10 tablets |
| Zita Met 50Mg/500Mg Tablet | $6.30/10 tablets |
What are the side effects of Siaglide M OD
The side effects of Siaglide M OD are:
- Headache
- Diarrhea
- Vomiting
- Stuffy or runny nose
- Indigestion
- Sore throat
They are temporary and will disappear as the body adjusts to the medication. However, if the symptoms continue or worsen, consult a doctor immediately.
Safety Advice
Liver disease
Siaglide M OD is not generally recommended for patients with liver disease. Liver dysfunction can interfere with the drug's metabolism and clearance, increasing the risk of Lactic Acidosis, a condition associated with Metformin, one of its active ingredients. Consult a doctor for appropriate treatment.
Kidney impairment
The medication is not generally recommended for patients with kidney impairment. The kidneys clear Metformin from the body, and kidney impairment can cause the ingredient to accumulate, increasing the risk of Lactic Acidosis, a rare but possibly life-threatening condition associated with Metformin. Consult a doctor for appropriate treatment.
Pregnancy and breastfeeding
Siaglide M OD is not typically recommended during pregnancy as limited data are available about whether there are adverse effects on the developing fetus. Consult a doctor to weigh in on the potential benefits and the possible risks. Similarly, nursing mothers should consult their doctor before taking the medication to weigh the benefits and risks.
Avoid
Avoid taking the medication if you are allergic to Sitagliptin and Metformin. Alcohol can cause unexpected fluctuations in blood sugar levels and enhance the effect of Metformin on lactate metabolism, risking Lactic Acidosis. Driving may be affected if blood sugar is too high or too low.
FAQs
Can I take Siaglide M OD if I have heart disease?
Siaglide M OD should be used with caution if you have heart disease. It is not recommended for patients with severe heart problems, such as acute heart failure or a recent heart attack. Always inform your doctor about your heart condition before starting this medication.
Should I inform my doctor before surgery or medical procedures?
Yes, always inform your doctor about your diabetes treatment before undergoing surgery or medical procedures, as you may need to adjust your medication temporarily.
Does Siaglide M OD cause vitamin B12 deficiency?
Yes, long-term use of Metformin (a component of Siaglide M OD) can reduce vitamin B12 levels in some people. Your doctor may advise regular monitoring and supplementation.
What should I do if I experience persistent nausea or vomiting while taking Siaglide M OD?
If you experience persistent nausea or vomiting, then it could be a sign of Lactic Acidosis or other serious side effects. Stop taking the medication and contact your doctor immediately for advice.
Can I take painkillers or antibiotics with Siaglide M OD?
Yes, you can take painkillers or antibiotics with Siaglide M. However, some painkillers (like NSAIDs) and certain antibiotics can interact with Metformin. It is essential to always inform your doctor about all medications, including over-the-counter drugs, to prevent any complications.