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Sitara-M 100/500 Tablet ER
What is Sitara M 100/500
Sitara M 100/500 is a combination antidiabetic medication that makes Type 2 Diabetes management more effective. This tablet contains two powerful active ingredients: Sitagliptin (100 mg) and Metformin (500 mg). These components work synergistically to provide blood glucose control.
Intas Pharmaceuticals Ltd is the leading manufacturer of Sitara M 100/500. Sitagliptin belongs to the Dipeptidyl Peptidase-4 (DPP-4) inhibitor class of medications. Metformin is classified as a biguanide antidiabetic agent.
Together, they address multiple pathways involved in glucose metabolism and Insulin regulation. Common side effects include nausea, diarrhea, abdominal discomfort, and headache. Most adverse reactions are temporary and resolve as the body adapts. Serious complications like Lactic Acidosis are rare but require immediate medical intervention.
Store this medication at room temperature, away from moisture and direct sunlight. Keep tablets in their original packaging until use. Never exceed prescribed dosages or share them with others. Regular blood sugar monitoring enhances treatment effectiveness.
What are the benefits of Sitara M 100/500
Sitara M 100/500 delivers dual-mechanism Diabetes control through complementary pathways. Sitagliptin enhances incretin hormone activity by inhibiting the DPP-4 enzyme degradation. This increases Insulin secretion when blood glucose levels are elevated and appropriately reduces glucagon release.
Metformin decreases hepatic glucose production while improving peripheral Insulin sensitivity. It reduces glucose absorption from the intestines and enhances cellular glucose uptake. The combination provides superior glycemic control compared to individual components.
Key advantages include reduced Hypoglycemia risk and weight-neutral effects. Patients experience consistent 24-hour blood sugar management. The combination allows lower individual doses while maintaining efficacy.
Simplified dosing regimens and improved tolerability profiles result in enhanced patient compliance. However, optimal results require adherence to prescribed diet and exercise recommendations.
How to take Sitara M 100/500
Sitara M 100/500 is a prescription medication that should be taken as per your doctor's instructions. Here are the general guidelines:
- Take twice daily with morning and evening meals.
- Swallow tablets whole with adequate water. Do not crush or chew.
- Maintain consistent timing and take with meals for optimal blood sugar control.
- Do not exceed 2 Sitara M tablets in 24 hours.
Strengths and substitutes
The strengths and substitutes available for Sitara M at Cheap Medicine Shop are:
| Sitara-M 50/500 Tablet ER | $5.40/10 tablets |
What are the side effects of Sitara M 100/500
Sitara M 100/500 is generally well-tolerated by most diabetic patients. However, it may cause side effects, including:
- Gastrointestinal upset
- Nausea
- Diarrhea
- Stomach cramping
- Metallic taste
- Appetite changes
- Headache and mild dizziness
These effects mostly do not require medical consultation and disappear as your body adjusts. See a doctor immediately if they persist.
Safety Advice
Liver disease
Use cautiously in patients with liver impairment or elevated liver enzymes. Regular liver function monitoring is essential during treatment. Based on liver function test results, dose modifications may be necessary. Discontinue if significant liver enzyme elevation occurs.
Kidney impairment
Contraindicated in severe kidney disease due to the Metformin component. Regular kidney function assessment is mandatory for safe use. Dose reduction is required in moderate kidney impairment. Stop medication if kidney function deteriorates significantly.
Pregnant and breastfeeding women
Not recommended during pregnancy due to limited data for combination therapy. Alternative Diabetes management strategies should be considered during pregnancy. Avoid during breastfeeding as medication transfer to breast milk is possible.
Avoid
Limit alcohol as it increases the possibility of Lactic Acidosis significantly. Avoid iodinated contrast agents without proper preparation. Discontinue before surgical procedures requiring general anesthesia.
FAQs
When should I take Sitara M 100/500 for best results?
Take the Sitara M tablet with meals to reduce gastrointestinal side effects and optimize absorption. Morning and evening doses should be spaced 12 hours apart. Consistent timing helps maintain steady blood glucose levels throughout the day.
Can I split or crush Sitara M 100/500 tablets?
No, never split, crush, or chew these tablets, as it affects medication release. Swallowing whole ensures proper absorption and therapeutic effectiveness. Contact the doctor if you have difficulty swallowing tablets for alternative options.
What foods should I avoid while taking this medication?
Maintain consistent carbohydrate intake and avoid high-sugar foods with this medicine. Limit alcohol consumption and avoid skipping meals. Follow your prescribed diabetic diet plan for optimal blood sugar management and medication effectiveness.
How long before I see improvements in blood sugar?
Initial improvements typically occur within one to two weeks of regular use. Significant glycemic control improvements are usually evident after four to six weeks. Maximum therapeutic benefits develop over eight to twelve weeks.
What should I do during illness or infection?
Monitor blood sugar more frequently during illness, as levels may fluctuate. Contact your healthcare provider for guidance on medication adjustments. Maintain hydration and continue taking medication unless specifically advised otherwise.