Sitaxa M 50mg/500mg Tablet
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CMS8495
What is Sitaxa M 50+500
Sitaxa M 50+500 contains Sitagliptin (50 mg) and Metformin (500 mg) as active pharmaceutical ingredients. This fixed-dose combination targets Type 2 Diabetes through complementary mechanisms of action.
The lower Sitagliptin dose makes it suitable for patients requiring moderate Dipeptidyl Peptidase-4 (DPP-4) inhibition. Torrent Pharmaceuticals Ltd manufactures Sitaxa M 50+500.
This combination medication addresses Insulin resistance and impaired Insulin secretion simultaneously. Sitagliptin belongs to the DPP-4 inhibitors, while Metformin is a biguanide class medication. Both components have established safety profiles in Diabetes management.
Frequent side effects include gastrointestinal disturbances, headache, and upper respiratory tract infections. Most reactions are mild and transient in nature. Rare but serious effects like Lactic Acidosis require immediate medical attention and discontinuation.
Proper storage at controlled room temperature preserves medication stability. Protect from excessive moisture and heat exposure. Keep out of children's reach always. Follow prescribed dosing schedules for optimal therapeutic outcomes.
What are the benefits of Sitaxa M 50+500
This combination provides Glycemic management through distinct yet complementary pathways. Sitagliptin selectively inhibits the DPP-4 enzyme, prolonging active Incretin hormone levels.
Enhanced GLP-1 and GIP activity stimulates glucose-dependent Insulin release while suppressing inappropriate glucagon secretion. Metformin primarily reduces hepatic glucose output and improves peripheral tissue Insulin sensitivity.
It decreases intestinal glucose absorption and enhances muscle glucose utilization. The combined effect provides better Hemoglobin A1c reduction than monotherapy approaches.
Additional benefits include minimal Hypoglycemia risk and cardiovascular safety. The combination supports weight maintenance without promoting weight gain. Flexible dosing options accommodate individual patient requirements and tolerance levels.
It is crucial to note that lifestyle modifications amplify therapeutic benefits significantly.
How to take Sitaxa M 50+500
Sitaxa M 50+500 is a prescription medication that should be taken as per your doctor's instructions. Here are the general guidelines:
- Take twice daily with breakfast and dinner.
- Swallow whole with a full glass of water.
- Space doses approximately 12 hours apart for consistency. Take with meals.
- Do not exceed prescribed daily dosage limits.
Strengths and substitutes
The strengths and substitutes available at Cheap Medicine Shop are:
| Sitaxa M XR 100+500 Tablet | $8.30/10 tablets |
What are the side effects of Sitaxa M 50+500
Sitaxa M 50+500 is generally safe for most Type 2 Diabetes patients. However, it may cause side effects, including:
- Stomach upset
- Nausea
- Loose stools
- Diarrhea
- Respiratory tract infections
- Joint discomfort
- Muscle pain
These adverse effects typically do not require medical consultation and disappear as your body adjusts.
Safety Advice
Liver disease
Generally safe in mild liver impairment with regular monitoring. Liver function tests should be performed before and during treatment. Dose adjustment may be considered for moderate liver disease. Avoid severe liver dysfunction or active liver disease.
Kidney impairment
Due to the Metformin component, careful evaluation before prescribing is required. Regular kidney function monitoring is essential throughout treatment. It is contraindicated in severe cases. A dose reduction is needed for moderate kidney impairment.
Pregnant and breastfeeding women
Safety during pregnancy has not been established for this combination. Alternative Diabetes management options are preferred during pregnancy. Breastfeeding mothers should avoid this medication as components may transfer to breast milk.
Avoid
Excessive alcohol intake significantly increases the chances of Lactic Acidosis. Avoid dehydration during illness or strenuous exercise. Inform healthcare providers before any diagnostic procedures involving contrast media.
FAQs
How does Sitaxa M 50+500 differ from higher-strength combinations?
This formulation contains a lower Sitagliptin dose suitable for patients requiring moderate DPP-4 inhibition. It provides effective glucose control with potentially fewer side effects. Your doctor determines the appropriate strength based on individual needs.
Can I take Sitaxa M 50+500 with other Diabetes medications?
Combination with other antidiabetic agents is possible under medical supervision. Your doctor will adjust doses to prevent Hypoglycemia and drug interactions. Regular blood sugar monitoring becomes more important with multiple medications.
What should I do if I experience persistent stomach problems?
Take medication with food to minimize gastrointestinal side effects. Contact the healthcare provider if symptoms persist beyond two weeks. Temporary dose reduction or alternative medications may be considered.
Is Sitaxa M 50+500 suitable for elderly patients?
Generally safe for elderly patients with appropriate monitoring. Age-related kidney function decline requires careful evaluation. Regular health assessments ensure continued safety and effectiveness in older adults.
How should I store Sitaxa M 50+500 tablets?
Store at room temperature between 20-25°C in original packaging. Protect from moisture, heat, and direct sunlight exposure. Keep medication away from children, and never use expired tablets.