Trajenta 5 Mg

What is Trajenta 5 mg

Trajenta 5 mg is an oral antidiabetic medication prescribed for Type 2 Diabetes mellitus in adults. Its primary ingredient is Linagliptin, which belongs to the Dipeptidyl Peptidase-4 (DPP-4) inhibitor class of drugs. Boehringer Ingelheim is the leading manufacturer of Trajenta.

Trajenta helps control blood sugar levels by increasing insulin production when blood glucose is high and reducing glucose production from the liver. It is usually prescribed when diet and exercise alone cannot control blood sugar levels.

Common side effects of Trajenta include upper respiratory tract infections, headache, and nasopharyngitis. Trajenta should be stored at room temperature, away from moisture and heat. It is generally well-tolerated but may not suit patients with a history of pancreatitis or hypersensitivity to Linagliptin.

Always consult a medical provider before starting or stopping this medication, especially if you have kidney or liver conditions.

What are the benefits of Trajenta 5 mg

Trajenta 5 mg works by inhibiting the DPP-4 enzyme, which generally breaks down incretin hormones. By blocking this enzyme, Trajenta allows these hormones to remain active longer, stimulating insulin release when blood sugar is high and decreasing glucagon secretion from the pancreas, thus reducing hepatic glucose production.

Key benefits include:

• Effective blood glucose control without causing Hypoglycemia when used alone.
• It has a weight-neutral profile, unlike some other Diabetes medications.
• Once-daily dosing that can be taken with or without food
• No dose adjustment is required for patients with kidney or liver impairment.

It is crucial to note that Trajenta is not used for type 1 Diabetes or diabetic ketoacidosis treatment and works best when combined with an appropriate diet and regular exercise.

How to take Trajenta 5 mg

Trajenta 5 mg is a prescription medication that should be taken as per your doctor's instructions. Here are the general guidelines:

• Take Trajenta 5 mg once daily at any time of day.
• Swallow the tablet whole with water.
• It can be taken with or without food.
• Do not exceed the recommended dose of one 5 mg tablet per day.

Strengths and substitutes

The strengths and substitutes available for Trajenta are:

What are the side effects of Trajenta 5 mg

Trajenta 5 mg is generally well-tolerated. However, it may cause side effects, including:

• Nasopharyngitis (common cold symptoms)
• Upper respiratory tract infection
• Headache
• Hypoglycemia (especially when combined with sulfonylureas)

These effects typically do not require medical attention and disappear as your body adjusts to the medication.

Safety Advice

Liver disease

Trajenta does not require dose adjustment in patients with mild to severe liver impairment. However, clinical studies in patients with severe liver dysfunction are limited. Regular liver function monitoring is recommended, and any unusual symptoms must be reported to the doctor.

Kidney impairment

One of the advantages of Trajenta is that no dose adjustment is required for patients with kidney impairment, including those with end-stage renal disease requiring hemodialysis. However, periodic kidney function monitoring is still advised during treatment. Consult a doctor before use.

Pregnant and breastfeeding women

Trajenta should be used during pregnancy only if needed and when the potential benefits justify the potential risks to the fetus. Limited data is available on its excretion in breast milk. Healthcare providers should weigh the benefits of breastfeeding against the possible adverse effects on the infant when prescribing Trajenta to nursing mothers.

Avoid

Avoid alcohol as it may affect blood glucose levels and potentially interact with Trajenta, so limit intake. Certain medications may interact with Trajenta, including strong inducers of CYP3A4 or P-glycoprotein. Also, avoid herbal supplements like St. John's Wort without consulting your doctor. Try not to skip meals, as this may increase the risk of Hypoglycemia, mainly with other Diabetes medications.