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Xet CR 12.5 is a controlled-release antidepressant used in the treatment of Depression and a range of anxiety-related disorders. It contains Paroxetine (12.5 mg), an FDA-approved Selective Serotonin Reuptake Inhibitor (SSRI), which works by raising serotonin levels in the brain to improve mood changes, minimize anxiety, and support emotional balance. Zydus Cadila manufactures the medicine in WHO-GMP-certified facilities.
By enhancing serotonin activity, Xet CR Tablet helps with conditions like Major Depressive Disorder (MDD), Obsessive-compulsive Disorder (OCD), Panic Disorder, Social Anxiety Disorder (SAD), Post-Traumatic Stress Disorder (PTSD), and Generalized Anxiety Disorder.
The tablet is usually taken once daily in the morning with food. As it is a controlled-release formulation, it should be consumed whole and not crushed, chewed, or broken into pieces. Any dose adjustment should be done only under a doctor’s supervision. If you miss a dose, take it as soon as possible, unless it is close to the next scheduled dose. Taking two doses together should be avoided. In case of overdose, immediate medical attention is necessary, especially if symptoms such as restlessness, tremors, fever, vomiting, rapid heartbeat, or muscle stiffness occur.
Common side effects may include nausea, dizziness, dry mouth, sleep disturbances such as insomnia or drowsiness, and possible weight gain. Medical advice should be sought promptly if severe side effects develop, including suicidal thoughts, signs of Serotonin Syndrome like agitation, confusion, or hallucinations, or allergic reactions like rash, swelling, or difficulty breathing.
Take caution during pregnancy and breastfeeding. The medicine may interact with certain drugs, including migraine treatments like Triptans, Tryptophan supplements, Monoamine Oxidase Inhibitors (MAOIs), Pimozide, and some antibiotics such as Linezolid.
The tablets are stored at a temperature lower than 30°C (86°F) in a cool, dry place, protected from moisture and direct sunlight.
The benefits of this SSRI antidepressant come from its ability to increase serotonin activity, which helps uplift mood, ease Anxiety, and promote emotional stability. That is,
Xet CR 12.5 is a prescription-only medicine and should be used strictly as directed by a doctor. General instructions for taking this medication include:
At the moment, no other strengths or substitute versions of Xet CR 12.5 are available at Cheap Medicine Shop. Several suitable alternative treatments are available for you to choose from. Always consult your doctor before making any changes to your treatment.
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Like any SSRIs, this Paroxetine tablet can cause specific side effects that are usually mild and tend to subside as the body adapts to the medicine. If these effects persist or become severe, seek medical advice promptly. Common side effects associated with Xet CR 12.5 Tablet include:
Liver Disease
Xet CR 12.5 should be used carefully in people with liver disease, as the liver breaks down Paroxetine. Reduced liver function can lead to higher levels of the medicine remaining in the body, which increases the risk of side effects. Dose modification and close medical supervision are recommended.
Kidney Impairment
In patients with kidney impairment, Xet CR 12.5 is prescribed with caution, as decreased kidney function can delay its clearance from the body and raise the likelihood of side effects. To ensure safety, doctors may adjust the dose and closely monitor the patient throughout the treatment course.
Pregnant and Breastfeeding women
Paroxetine may pose a risk to an unborn baby, so patients should tell their doctor if they are pregnant or planning a pregnancy. Additionally, it can also pass into breast milk, making it essential to inform the doctor if breastfeeding or planning to breastfeed. The healthcare provider will assess whether its use is safe during pregnancy or while nursing.
Avoid
Do not take this medicine if you are allergic to Paroxetine. Avoid alcohol, as it can worsen drowsiness, dizziness, and reduce effectiveness. Do not drive or operate any machinery due to reduced alertness. Additionally, do not take grapefruit or grapefruit juice, as it can increase side effects by affecting how the medication is metabolized.
Yes, Xet CR 12.5 is generally safe for long-term use under a doctor’s supervision. Regular medical check-ups are essential for monitoring effectiveness, managing any side effects, and adjusting the dosage as needed, ensuring continued safe and effective treatment.
Xet CR is generally not recommended for patients below 18, as its safety and effectiveness have not been established. Teenagers face increased risks of suicidal thoughts, agitation, hostility, or mania. In severe cases like OCD, specialists may prescribe it with strict monitoring if the benefits outweigh the risks.
No, you should not switch brands of Paroxetine without consulting your doctor. Different brands may have varying release mechanisms or inactive ingredients, which can affect effectiveness or cause side effects. Always consult a healthcare provider before making any changes to ensure safe and consistent treatment.
No, Xet CR 12.5 does not provide immediate relief. It typically takes 1-2 weeks to notice initial improvements, with full benefits becoming apparent after several weeks of consistent use. Patience and regular intake, as prescribed by your doctor, are essential for effective treatment.
Yes, Xet CR can cause weight gain in some people, particularly with higher doses or long-term use beyond six months. It may also affect appetite and eating habits. While not everyone experiences this, Paroxetine is among the SSRIs more likely to cause weight changes.
Yes, elderly patients can use Xet CR 12.5, but caution is advised. Doctors may monitor for side effects more closely, adjust the dose as needed, and regularly assess overall health to ensure a safe and effective treatment.
Xet CR (Paroxetine controlled-release) usually shows initial improvements within 1-2 weeks, but full effects for Depression or Anxiety may take 4-8 weeks. Anxiety may improve sooner, while OCD or PTSD can take 8–12 weeks. Response varies by dose, condition, metabolism, and concurrent treatments, so consistent use and monitoring are essential.
