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Exermet 1000 is a potent oral anti-diabetic medicine prescribed for Type 2 Diabetes Mellitus in adults, particularly when lower doses have proven insufficient. Its primary ingredient is Metformin Hydrochloride in a 1000 mg sustained-release formulation, which belongs to the biguanide class of anti-hyperglycemic agents.
Cipla Ltd. is the leading manufacturer of Exermet in India. This medication helps maintain optimal blood glucose levels by enhancing Insulin sensitivity, reducing hepatic glucose production, and decreasing intestinal glucose absorption.
Common side effects of Exermet include digestive discomfort such as nausea and diarrhea, which usually subside with use. Rare but serious side effects include lactic acidosis, particularly in patients with kidney dysfunction.
Exermet should be stored in a cool, dry place away from direct sunlight and moisture. Before beginning treatment, patients should inform their healthcare provider about all existing medical conditions and medications. This medication is not suitable for patients with severe kidney disease, liver problems, or metabolic acidosis.
Exermet 1000 provides extended-release Metformin therapy, allowing for sustained glucose control over 24 hours. It works by improving Insulin sensitivity in muscle and fat tissues while simultaneously reducing glucose production in the liver and slowing intestinal absorption of carbohydrates.
Key benefits of Exermet include:
It is crucial to note that Exermet should be used alongside lifestyle modifications, including regular physical activity and appropriate dietary changes, for optimal Diabetes management.
Exermet tablet is a prescription medication that should be taken per your doctor's instructions. Here are the general guidelines:
The strengths and substitutes available for Exermet are:
| $1.2/10 Tablets | |
| $1.5/10 Tablets | |
| $2.7/10 Tablets |
Exermet tablet is generally well-tolerated. However, it may cause side effects, including:
These adverse effects diminish over time as your body adjusts to the medication. The sustained-release formulation helps reduce the intensity of gastrointestinal side effects compared to immediate-release Metformin preparations.
Liver disease
Exermet is contraindicated in patients with liver disease as impaired hepatic function increases the risk of lactic acidosis. Regular liver function tests should be performed before and periodically during treatment. Patients with elevated liver enzymes should consider alternative medications.
Kidney impairment
Metformin is primarily eliminated through the kidneys. Exermet is contraindicated in patients with severe kidney impairment and requires dose adjustment for moderate impairment. Regular monitoring of kidney function is essential, with testing recommended at least annually.
Pregnant and breastfeeding women
Insulin is generally the preferred treatment for managing Diabetes during pregnancy. Limited data exists on Exermet's safety during pregnancy. If considering use during pregnancy, the potential benefits should outweigh the risks. Small amounts of Metformin pass into breast milk but are considered safe for nursing infants. Consult your healthcare provider before use.
Avoid
Avoid alcohol to reduce the risk of lactic acidosis. Temporarily stop Metformin before iodinated contrast scans. Use caution with drugs like Cimetidine, Furosemide, and Trimethoprim. Limit high-carb foods to maintain blood sugar control.
Yes, Exermet 1000 can be used in combination with other anti-diabetic medications. However, such combinations should only be used under medical supervision to avoid potential Hypoglycemia or other interactions.
Type 2 Diabetes typically requires lifelong management. Exermet is usually a long-term treatment. Regular follow-ups with your doctor will determine ongoing therapy based on your blood glucose control.
Temporarily, stop taking Exermet and contact your healthcare provider immediately. Severe dehydration from prolonged diarrhea or vomiting can increase the risk of lactic acidosis, requiring prompt medical attention.
When used alone, Exermet rarely causes Hypoglycemia. However, the risk increases when combined with other anti-diabetic medications, especially Insulin or sulfonylureas. Always monitor blood glucose regularly and be aware of Hypoglycemia symptoms.
Yes, Exermet alone doesn't usually cause dizziness or affect alertness. However, if you're taking it with other medications that may cause Hypoglycemia, monitor your blood glucose before driving to ensure safety.
