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Manocol 400 is a delayed-release oral medication used to treat Inflammatory Bowel Diseases (IBDs) such as Ulcerative Colitis and Crohn's ileo-colitis. It contains the FDA-approved active ingredient Mesalamine (Mesalazine) 400 mg, a member of the aminosalicylate group of anti-inflammatory drugs. Cmg Biotech Ltd, a GMP-certified company, manufactures Manocol 400.
Mesalamine acts locally on the intestinal lining by minimizing the production of inflammatory mediators such as prostaglandins and leukotrienes. It helps decrease inflammation, supports healing of the bowel lining, and lowers the risk of disease flare-ups. It is primarily prescribed for mild to moderate Ulcerative Colitis and for maintaining remission in Crohn's ileo-colitis.
Consume the pill whole with water, without breaking it. For active disease, adults usually take 2.4 gm daily; the maintenance dose ranges from 1.2 gm to 2.4 gm per day, taken once or in divided doses. Adequate fluid intake is essential, and the treatment should be continued as advised by the doctor. For a missed dose, take it as soon as possible unless it is nearly time for the next dose. Never take a double dose. In case of an overdose, seek immediate medical care.
Common side effects of this medication are headache, nausea, stomach pain, diarrhea, and gas. Urgent medical attention is needed if symptoms such as severe allergic reactions, bloody stools, yellowing of the skin or eyes, reduced urine output, or intense abdominal pain occur. Use the medicine cautiously in patients with kidney or liver problems and in elderly individuals. Avoid this medicine if you are allergic to salicylates. Mesalamine can interact with medicines like Azathioprine, Warfarin, and NSAIDs.
Store Manocol 400 tablets at 20°C to 25°C, protected from heat, moisture, and light, in their original packaging. Keep it out of reach of children and pets.
Manocol 400 provides several benefits for individuals with Inflammatory Bowel Syndrome (IBS). They are:
Manocol 400 is a prescription medication that patients should take under a healthcare professional's guidance. To achieve consistent results, follow these general guidelines:
Currently, Cheap Medicine Shop stocks only the 400 mg strength of Manocol Tablet DR. Other alternative medicines containing the same active ingredient are available and can be appropriate depending on your condition. Always consult your doctor before switching to any substitute.
| Mesacol 400 mg | $4.80/10 pills |
| Mesazed 400 mg Tablet | $4.50/10 pills |
This gut anti-inflammatory medicine is generally well-tolerated when taken as prescribed. However, some people may experience side effects, particularly during the initial phase of treatment. They are usually mild and tend to improve as the body adjusts to the medication. Common Manocol 400 side effects include:
However, if the effects continue or worsen, consult your doctor immediately.
Liver Disease
People with liver conditions should use Manocol 400 cautiously, as it may affect liver function. Dose adjustments may be required, and regular liver enzyme tests are advised. Seek medical attention if symptoms such as discoloration of the skin or eyes, or unusual fatigue, occur.
Kidney Impairment
Patients with kidney problems should take this medicine with care. It is not recommended for those with severe kidney failure due to the risk of kidney damage, including interstitial nephritis. Kidney function tests, such as serum creatinine, should be done before starting treatment and monitored regularly.
Pregnant and Breastfeeding women
Pregnant women must consult a doctor before using Manocol 400, as there may be potential risks to the unborn baby. It should only be used if the benefits outweigh the risks. Breastfeeding mothers should also be cautious, as the medicine can pass into breast milk and may cause diarrhea in infants.
Avoid
Do not take this medicine if you are allergic to Mesalamine. Avoid consuming alcohol, as it can irritate the digestive system, worsen IBD symptoms, and increase the risk of side effects, including liver-related problems.
Yes, Manocol 400 Tablet can be taken once daily in some cases, depending on the dose prescribed by your doctor. For maintenance therapy, the total daily dose may be taken as a single dose or divided. Always follow your doctor's instructions for the best results.
Yes, Manocol 400 Tablet is safe to take with antibiotics. There are no significant interactions or safety concerns when taken with common antibiotics like Amoxicillin or Ciprofloxacin. Always consult a doctor to prevent unwanted complications.
You should store the Manocol 400 tablets at room temperature between 20 °C and 25 °C in their original packaging. Always protect it from heat, moisture, and sunlight to maintain its effectiveness. Also, keep it away from children and pets.
Yes, elderly patients can take Manocol 400 tablets safely under a healthcare professional's guidance. Since older adults may be more sensitive to side effects, regular health monitoring and routine check-ups are recommended.
No, you should not stop Manocol 400 Tablet suddenly without consulting your doctor. Stopping it abruptly may lead to a flare-up of your symptoms. Always follow your healthcare provider's guidance when changing or stopping your treatment.
No, Manocol 400 Tablet does not usually cause stomach ulcers. It is designed to act in the intestines, not the stomach. However, if you experience severe stomach pain, bleeding, or unusual symptoms, consult your doctor.
No, Mesalazine is not a steroid. It is an anti-inflammatory medicine in the aminosalicylate (5-ASA) class and is used to manage Inflammatory Bowel Diseases such as Ulcerative Colitis.
