Apxban 5 mg
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SKU
CMS9016
What is Apxban 5 mg
Apxban 5 mg is an oral anticoagulant used to prevent Stroke and systemic embolism in individuals with non-valvular Atrial Fibrillation (irregular heartbeat which increases the risk of blood clots). It is also used to treat and prevent recurrence of Deep Vein Thrombosis (blood clots in deep veins) and Pulmonary Embolism (a clot that travels to the lungs). Additionally, it helps prevent DVT after hip or knee replacement surgery.
The medicine is manufactured by Care Formulation Labs Pvt Ltd in GMP-compliant facilities. It contains FDA-approved Apixaban (5 mg), a Factor Xa inhibitor. It works by blocking Factor Xa (a clotting protein in the blood), which slows down the clotting process and reduces the formation of harmful blood clots while still allowing normal clotting needed for wound healing.
It is usually taken twice daily, with or without food, as prescribed. The duration of Apixaban treatment depends on the condition being treated. Long-term use is common in Atrial Fibrillation, while shorter courses are used after surgery.
Common side effects include easy bruising, mild bleeding, and nausea. Since this medicine reduces blood clotting, the most important risk is bleeding. Seek medical attention if there is unusual bleeding, blood in urine or stools, coughing blood, or a severe headache.
Inform a doctor about any bleeding disorders, liver disease, pregnancy, or use of other blood thinners before starting treatment. Store Apxban tablets below 25°C in a cool place, away from sunlight and moisture. Keep out of reach of children.
What are the benefits of taking Apxban 5 mg
Apxban 5 mg helps prevent the formation of harmful blood clots by slowing down the clotting process. This lowers the risk of serious complications such as Stroke and blocked blood vessels. It is commonly used for:
- Preventing Stroke in people with non-valvular Atrial Fibrillation
- Treating and preventing Deep Vein Thrombosis
- Treating and preventing recurrence of Pulmonary Embolism
- Preventing blood clot formation after hip or knee replacement surgery
How to take Apxban 5 mg
Apxban 5 tablet is a prescription medication that should be used as directed by a healthcare professional. Here are the general guidelines:
- Take a tablet twice daily, approximately 12 hours apart, at the same times each day, as prescribed by a doctor.
- Swallow the tablet whole with a glass of water.
- Apxban 5 mg may be taken with or without food.
- Do not exceed the prescribed dosage and do not stop taking this medicine abruptly, as stopping anticoagulant therapy significantly increases the risk of Stroke or clot formation.
Strengths and Substitutes
Apxban is currently available as a single strength option at Cheap Medicine Shop. However, you can consider the following alternatives:
| Apivas 2.5 Tablet | $7.40/10 tablets |
| Apigat 5 Tablet | $9.60/10 tablets |
What are the side effects of Apxban 5 mg
Like any medication, Apxban 5 mg can cause some side effects. Consult a healthcare professional if any of the following persist or worsen:
- Easy bruising
- Minor bleeding from cuts that takes longer than usual to stop
- Nausea
- Anemia (low red blood cell count)
- Blood in urine (pink or brown discoloration)
- Unusual fatigue
- Skin rash
Safety Advice
Liver Disease
Apxban 5 tablet is contraindicated in patients with severe liver disease, particularly those with coagulopathy (impaired clotting function), as adding an anticoagulant significantly raises the risk of life-threatening bleeding. People with mild to moderate liver disease can use Apxban 5 mg with caution and under close medical monitoring.
Kidney Impairment
Apxban 5 mg should be used with caution in patients with kidney disease. Apixaban is partially eliminated via the kidneys, and impaired kidney function can increase medicine levels in the blood, raising the risk of bleeding. Dose adjustment may be required based on the degree of impairment, creatinine clearance, age, and body weight. Regular kidney function monitoring is recommended during therapy.
Pregnant and Breastfeeding women
Apxban 5 mg is not recommended during pregnancy. Anticoagulants increase the risk of pregnancy-related bleeding complications, and Apixaban may cross the placenta, affecting fetal clotting. Consult a doctor immediately if pregnancy occurs during treatment. Apixaban is not recommended during breastfeeding. Consult a doctor for a safe alternative anticoagulant if needed.
Avoid
Do not use Apxban 5 mg in patients with active clinically significant bleeding or conditions that predispose to major bleeding, such as recent brain or spinal surgery. Avoid concurrent use with other anticoagulants, strong antiplatelet agents, or thrombolytic medicines without close medical supervision, as the combination significantly increases bleeding risk. Inform a doctor of all current medications before starting Apxban.
FAQs
How does Apxban 5 mg prevent Stroke in Atrial Fibrillation?
In Atrial Fibrillation, the irregular heartbeat causes blood to pool in the heart and form clots that travel to the brain and cause a Stroke. Apixaban blocks Factor Xa, interrupting the clotting process before a clot forms. This significantly reduces the risk of Stroke in patients with this condition.
Can Apxban 5 mg be taken long-term?
Yes, for patients with non-valvular Atrial Fibrillation, long-term use is typically required to maintain ongoing Stroke prevention. Regular medical review, kidney function monitoring, and bleeding risk assessment are recommended throughout extended therapy.
Does Apxban 5 mg increase the risk of bleeding?
Yes, as an anticoagulant, Apxban reduces the blood's ability to clot, which means cuts and minor injuries can bleed for longer than usual. More serious internal bleeding is a potential risk. Any signs of unusual, prolonged, or unexplained bleeding should be reported to a doctor immediately for assessment.
Are there any food or drug interactions with Apxban 5 mg?
Yes, Apixaban's blood levels are affected by strong CYP3A4 inhibitors, such as Ketoconazole and Ritonavir, which increase bleeding risk, and by strong inducers, such as Rifampicin, which reduce its effectiveness. Always inform a doctor of all medicines and supplements being taken concurrently to ensure safety.
What should I do if I miss a dose of Apxban 5 mg?
If you miss a dose of Apxban 5 mg, take it as soon as you remember on the same day. Do not double the dose to make up for a missed one. Continue with the regular schedule to maintain consistent anticoagulant effects.
Can I stop taking Apxban 5 mg on my own?
No, you should not stop taking Apxban 5 mg without medical advice, as it can increase the risk of blood clot formation, including Stroke. Always consult a doctor before discontinuing, as an alternative anticoagulant or gradual plan may be required.
Is Apxban 5 mg safe before surgery or dental procedures?
No, Apxban may need to be temporarily stopped before surgery or dental procedures to reduce bleeding risk. The timing depends on kidney function and procedure type. Always inform your doctor or dentist in advance for proper guidance.
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