Arvast F 5 Tablet

What is Arvast F 5 tablet

Arvast F 5 is a combination medication used to manage abnormal lipid levels in adults with high cholesterol and triglycerides. Its primary ingredients are Fenofibrate (67mg) and Rosuvastatin (5mg), which belong to fibric acid derivatives and statin classes of lipid-lowering medications, respectively.

This dual-action formulation effectively reduces LDL (bad) cholesterol and triglycerides while increasing HDL (good) cholesterol levels. Arvast F is prescribed when diet, exercise, and single-drug therapy are insufficient to achieve target lipid levels.

Common side effects of the tablet may include muscle pain, headache, digestive discomfort, and elevated liver enzymes. Regular liver function monitoring and muscle symptoms are recommended during treatment. Intas Pharmaceuticals Ltd is the leading manufacturer of Arvast, ensuring high-quality standards and consistent efficacy in cardiovascular health management.

What are the benefits of Arvast F 5 tablet

Arvast F 5 combines the complementary actions of Fenofibrate and Rosuvastatin to provide comprehensive lipid management. Rosuvastatin works by inhibiting HMG-CoA reductase, an enzyme critical for cholesterol production in the liver, thereby reducing LDL cholesterol levels.

Fenofibrate activates Peroxisome Proliferator-Activated Receptors (PPARs), enhancing the breakdown of triglycerides and increasing HDL cholesterol production.

This combination offers several advantages:

• More effective reduction of LDL cholesterol than either component alone.
• Significant decrease in triglyceride levels.
• Increase in beneficial HDL cholesterol.
• Reduced risk of atherosclerosis and cardiovascular events.
• The convenience of single-tablet administration.

It is crucial to note that the Arvast should be used as part of a comprehensive approach to cardiovascular health, including dietary changes, regular exercise, and lifestyle modifications.

How to take Arvast F 5 tablet

Arvast F 5 is a prescription medication that should be taken per your doctor's instructions. Here are the general guidelines:

• Take Arvast once daily, preferably in the evening. Take at the same time each day to maintain consistent blood levels.
• Swallow the tablet whole with a glass of water without crushing or chewing it.
• It can be taken with or without food, but try to take it at the same time each day for the best results.
• Do not exceed 1 tablet in 24 hours unless specifically directed by your doctor.

Strength and substitutes

The strength and substitutes available for Arvast F 5 are:

View all substitutes

What are the side effects of Arvast F 5 tablet

Arvast F 5 is generally well-tolerated. However, it may cause side effects, including:

• Muscle pain, tenderness, or weakness
• Headache and dizziness
• Nausea, indigestion, or abdominal discomfort
• Mild skin rash
• Elevated liver enzymes

These effects typically do not require medical consultation and often diminish as your body adjusts to the medication. However, severe muscle pain, yellowing of skin or eyes, unusual fatigue, or dark-colored urine should be reported to your doctor immediately.

Safety Advice

Liver disease

Arvast is metabolized in the liver and may cause elevation in liver enzymes. People with active liver disease or unexplained elevations in liver enzymes should not take this medication. Regular liver tests are recommended during treatment, especially during the first year. Dose reduction or discontinuation may be necessary if liver enzymes become significantly elevated.

Kidney impairment

Patients with mild to moderate kidney disease should use Arvast cautiously, often with dose adjustments. Those with severe kidney impairment (creatinine clearance <30 mL/min) should avoid this medication due to the increased risk of rhabdomyolysis. Regular kidney function monitoring is recommended during treatment.

Pregnant and breastfeeding women

Arvast is contraindicated during pregnancy as statins may harm the developing fetus, particularly affecting fetal lipid metabolism and development. Women of childbearing age should use contraception during treatment. This medication is also contraindicated during breastfeeding as both components can pass into breast milk and potentially affect the infant.

Avoid

Avoid grapefruit and its juice as it can increase the concentration of Rosuvastatin in the blood, potentially leading to side effects. Limit alcohol consumption as it may increase the risk of liver problems. Avoid strenuous exercise while taking this medication, especially if you experience muscle pain, as it may increase the risk of muscle injury.