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Istamet XR 500 Tablet
What is Istamet XR 500
Istamet XR 500 is an oral medication that combines two powerful antidiabetic FDA-approved agents: Sitagliptin (100 mg), a DPP-4 Inhibitor, and Metformin (500 mg), a Biguanide. This combination helps effectively control blood sugar in patients with Type 2 Diabetes Mellitus. Sun Pharmaceutical Industries Ltd manufactures the product.
Metformin reduces the liver's glucose production and improves the body’s sensitivity to Insulin. At the same time, Sitagliptin increases insulin release and lowers glucagon levels after meals, helping control both fasting and post-meal blood sugar.
Common side effects of this medicine include diarrhea, upset stomach, vomiting, and headache. Some may also experience low blood sugar (Hypoglycemia) if taken alongside other antidiabetic medications like Insulin or Sulfonylureas. It is handy to keep sugary food such as candy or juice in such cases. Alcohol can cause sudden changes in blood sugar levels, which patients should avoid. Other significant interactions include diseases like liver and kidney disease.
To maintain its effectiveness, keep the tablet in its original package at room temperature (below 30°C) and protect it from moisture. Do not stop taking the medication without your doctor’s guidance, as this may cause a sudden spike in blood sugar levels. Regularly monitor your blood glucose to ensure proper dosing and effective diabetes control.
What are the benefits of taking Istamet XR 500
The primary benefits of taking Istamet XR are effective and comprehensive blood sugar control for adults with Type 2 Diabetes Mellitus. This medicine combines Metformin and Sitagliptin, which work together to lower high blood sugar levels by improving Insulin sensitivity, increasing insulin release after meals, and reducing excess sugar production by the liver.
Consistent use of Istamet XR helps prevent serious complications of Diabetes, such as kidney damage (nephropathy), nerve problems (neuropathy), vision loss (retinopathy), diabetic foot ulcers, and delayed wound healing. Maintaining stable blood glucose levels also reduces the risk of significant Cardiovascular events like stroke and heart attack.
Unlike some other diabetes medications, Istamet XR generally does not cause weight gain during prolonged use, making it a favorable choice for many patients. Combined with a healthy diet and constant exercise, this medication supports better long-term Diabetes management and helps patients lead healthier, more active lives.
How to take Istamet XR 500
This medication is prescription-based, and patients should take it per the doctor’s instructions. Here are some general guidelines for this medication.
- Take the dose as directed by the doctor.
- Swallow the tablet with water. Do not crush or chew it.
- Take it with food to prevent an upset stomach.
- Take it at a fixed time daily.
Strengths and Substitutes
The strengths and substitutes of Istamet XR 500 available at Cheap Medicine Shop are:
| Istamet XR Tablet | $7.80/10 tablets |
What are the side effects of Istamet XR 500
The side effects of Istamet XR 500
- Headache
- Diarrhea
- Vomiting
- Stuffy or runny nose
- Indigestion
- Sore throat
They are temporary and will disappear as the body adjusts to the medication. However, if the symptoms continue or worsen, consult a doctor immediately.
Safety Advice
Liver disease
This medication is typically not advised for patients with liver disease, as impaired liver function can affect how the body processes and clears the drug. It will heighten the risk of Lactic Acidosis, a rare but potentially life-threatening side effect linked to Metformin. Patients should speak with a doctor to determine a safe and suitable treatment plan.
Kidney impairment
This medication is usually not recommended for individuals with kidney impairment. Since Metformin is eliminated through the kidneys, reduced kidney function can result in its buildup in the body, heightening the risk of Lactic Acidosis, a rare but serious side effect. Consult a doctor to explore safe treatment alternatives.
Pregnancy and breastfeeding
Istamet XR 500 is typically not advised during pregnancy due to limited information on its potential effects on the unborn baby. It’s crucial to consult a doctor to assess the possible risks and benefits. Breastfeeding mothers should also seek a doctor's advice before using this medication to ensure its safety for both mother and child.
Avoid
Avoid taking the medication if you are allergic to Sitagliptin and Metformin. Alcohol can cause unexpected changes in blood sugar levels and heighten the effect of Metformin, risking Lactic Acidosis. Driving may be affected if blood sugar is too high or too low.
FAQs
Can I stop taking Istamet XR 500 once my blood sugar is controlled?
No, you should not stop taking this medicine without consulting your doctor, even if you feel better. Stopping suddenly can cause your blood sugar to rise and increase the risk of Diabetes complications.
What dietary changes should I make while taking Istamet XR 500?
To optimize the effectiveness of Istamet XR, it is essential to make healthy lifestyle changes. Maintaining a nutritious diet, following physical activity, and eating regular meals can result in better Diabetes management. Always follow your doctor’s advice for a personalized dietary and exercise plan.
What will happen if I overdose on Istamet XR 500?
Overdosing on Istamet XR is dangerous and can lead to serious, potentially life-threatening complications. The most significant risk is Lactic Acidosis, a rare but severe condition where lactic acid builds up in the blood.
Can I take other medicines along with Istamet XR 500?
Yes, you can take other medicines along with Istamet XR. However, several medications, such as other antidiabetics, antibiotics, and Diuretics, can cause side effects like Hypoglycemia (low blood sugar levels). Inform your doctor of all the medicines you take to prevent complications.
What are the signs of low blood sugar, and what should I do?
Symptoms of low blood sugar include increased hunger, sweating, shakiness, weakness, or irregular heartbeat. If you experience these, immediately consume a sugary snack or drink and inform your doctor if symptoms persist.