Itral Ointment 3 gm
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What is Itral 3 gm
Itral Eye Ointment 3 gm is a topical antifungal ophthalmic preparation used for the treatment of fungal eye infections. It contains Itraconazole 1% (w/w), which belongs to the broad-spectrum azole antifungal class. It is manufactured by Jawa Pharmaceuticals Pvt Ltd in GMP-certified facilities.
Itraconazole inhibits fungal ergosterol synthesis, an essential component of the fungal cell membrane. By disrupting cell membrane formation, it prevents fungal growth and leads to fungal cell death. Itral Eye Ointment is thus used to treat ocular conditions such as Fungal Keratitis, Mycotic corneal Ulcer and Fungal Blepharitis.
The dosing schedule and duration of treatment depend on the severity of the fungal infection and will be decided by your ophthalmologist. Apply a small ribbon of ointment inside the lower eyelid, preferably at nighttime for maximum coverage and absorption. Avoid skipping any doses, and never double the dose to make up for missed ones.
Temporary irritation, mild redness, or blurred vision may occur after application. These side effects are usually short-lasting. Avoid wearing contact lenses while using Itral eye ointment to prevent further irritation. However, severe pain, persistent irritation, or visual changes require immediate medical attention.
Itral Eye Ointment should not be used by individuals allergic to Itraconazole or other azole antifungals. It should be used cautiously in pregnant or breastfeeding women and only under medical supervision. Avoid contact with the nose, mouth, or non-affected areas. If accidental contact does occur, rinse thoroughly with water.
Store Itral Eye Ointment 3 g below 30°C in a cool, dark place. Keep the tube tightly closed. Do not use beyond the expiry date and discard the ointment once it expires.
What are the benefits of taking Itral 3 gm ointment
Itral Eye Ointment is effective against multiple pathogenic fungi responsible for ocular fungal infections. Its key benefits and uses include:
- Fungal Keratitis treatment: It helps manage fungal infections affecting the cornea by inhibiting fungal growth and promoting healing.
- Corneal fungal ulcer therapy: Itral is prescribed for Mycotic Corneal Ulcers, wherein deeper fungal invasion requires prolonged surface retention.
- Fungal Blepharitis: This topical therapy is also effective against fungal infections involving the eyelid margins.
- Prolonged ocular surface contact: Research shows that the ointment formulation enhances retention and medication availability, especially in anatomically challenging regions of the eye.
Although oral Itraconazole is FDA approved for systemic fungal infections, its ophthalmic preparations are generally considered off-label or compounded formulations. These are advised in specialized fungal cases, especially when first-line treatments such as Natamycin fail.
How to use Itral 3 gm Eye Ointment
Use Itral Eye Ointment exactly as prescribed by your ophthalmologist. General instructions include:
- Wash your hands before and after application.
- With your head tilted backwards, pull down your lower eyelid.
- Apply a small ribbon of ointment inside the eyelid.
- Close the eye for 1-2 minutes to allow proper distribution.
- Wipe off any excess ointment from the surrounding skin with a clean tissue.
- Do not use other medications in the same eye for at least 10-15 minutes.
Strengths and Substitutes
Itral is available as a 1% (w/w) eye ointment in a 3 gm tube. Cheap Medicine Shop also offers other Itraconazole-based options at affordable prices, such as:
| Itral 5 ml Eye Drops | $ 6.29/ bottle |
What are the side effects of Itral 3 gm Eye Ointment
Itral eye ointment side effects are usually mild and temporary. These may include:
- Eye irritation
- Burning sensation
- Redness of the eye
- Itching around the eyelid
- Blurred vision
- Watery eyes
Rare but severe side effects may include persistent eye pain, redness, vision changes, eyelid swelling, or an allergic reaction. Seek immediate medical help if any of these occur.
Safety Advice
Liver disease
Itraconazole acts locally when used as an ophthalmic ointment and has minimal systemic absorption. Dose adjustment is generally not required under medical supervision.
Kidney impairment
Since systemic (whole-body) exposure is minimal, no dose adjustment is typically required in patients with kidney impairment. Use cautiously in prolonged therapy and consult your doctor if you have Chronic Kidney Failure.
Pregnant and breastfeeding women
Due to limited safety studies in this group, if you are pregnant, breastfeeding, or planning to conceive, consult your healthcare provider before use.
Avoid
Do not use if you are allergic to Itraconazole or other azole antifungal drugs. Avoid contact with the nose, mouth, or unaffected areas. Do not wear lenses during an active fungal infection. Do not use Itral Ointment 3 gm for viral or bacterial eye infections.
FAQs
How does Itral eye ointment work?
Itral Eye Ointment contains Itraconazole, an azole antifungal drug. It works by inhibiting ergosterol synthesis, an essential component of the fungal cell membrane. This disrupts fungal cell structure, prevents growth, and helps eliminate fungal infections such as Keratitis and Corneal Ulcers.
How long does it take for Itraconazole ophthalmic ointment to work?
Itraconazole usually begins working within 2-3 days, and you should see improvement in your symptoms. But complete healing of fungal ulcers or eyelid infections can take 4 to 6 weeks. The exact duration depends on the severity of the infection and the timely beginning of treatment.
Can I use Itral eye ointment 3 g for bacterial eye infections?
No, Itral Eye Ointment is formulated only for fungal infections. It does not treat bacterial or viral eye infections. Using it for non-fungal conditions may delay appropriate treatment and worsen the infection.
Can I wear contact lenses while using Itral eye ointment?
No, you should not wear contact lenses during an active eye infection or while using Itral Eye Ointment. Wearing lenses can worsen irritation and delay healing, and, thus, is not recommended.
Is it safe to use Itraconazole while breastfeeding?
Yes, topical ophthalmic Itraconazole is generally safe while breastfeeding, as it has minimal absorption into the bloodstream. However, due to limited safety studies, use it only if prescribed. Make sure to discuss both the benefits and potential risks with your doctor.
Should I refrigerate Itral eye ointment?
No, you should not refrigerate Itral Eye Ointment. It can be stored at room temperatures below 30°C in a cool, dark place. Keep the tube tightly closed and away from direct sunlight.
When should I dispose of Itral eye ointment?
You should discard Itral eye ointment after the expiry date, as printed on the label. You should dispose of all medications if you suspect contamination or if they begin to feel or smell weird.