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Onglyza 5mg Tablet
What is Onglyza 5
Onglyza 5 delivers targeted treatment for Type 2 Diabetes through its active ingredient, FDA-approved Saxagliptin 5 mg. This Dipeptidyl Peptidase-4 (DPP-4) inhibitor medication regulates blood sugar by enhancing incretin hormone activity. It explicitly targets glucose-dependent Insulin release mechanisms.
AstraZeneca developed this medicine. It selectively inhibits DPP-4 enzyme activity, preserving incretin hormones like GLP-1 and GIP for extended periods.
Reported side effects include Nasopharyngitis, headache, and urinary tract infections. Some patients experience peripheral edema. Hypersensitivity reactions occur rarely but require immediate medical attention.
Store at room temperature between 15-30°C in the original blister packaging. Avoid exposure to excessive moisture and heat. Keep away from children and pets. Check expiration dates regularly before use. Professional medical guidance is essential for safe administration. Regular blood glucose monitoring optimizes treatment effectiveness.
What are the benefits of Onglyza 5
Onglyza 5 operates by selectively inhibiting DPP-4 enzyme activity in the intestinal system. This inhibition prevents the rapid degradation of incretin hormones. The preserved hormones stimulate glucose-dependent Insulin secretion from pancreatic beta cells.
Key therapeutic benefits include:
- Glucose-dependent Insulin release without Hypoglycemia risk
- Suppressed glucagon secretion during hyperglycemic states
- Minimal impact on body weight
The medication demonstrates excellent tolerability profiles across diverse patient populations. It works synergistically with lifestyle interventions, including diet and exercise. Combination therapy with Metformin or Insulin shows enhanced glycemic control compared to individual treatments.
How to take Onglyza 5
Onglyza is a prescription medication requiring healthcare professional supervision. Here are the general guidelines:
- Take an Onglyza tablet once daily, regardless of meal timing.
- Swallow the tablet whole with water without chewing.
- Maintain a consistent daily administration schedule. Take with or without food.
- Do not exceed 1 tablet within 24 hours unless prescribed.
Strengths and substitutes
The strengths and substitutes available for Onglyza 5 at Cheap Medicine Shop are:
| Onglyza 2.5mg Tablet | $16.00/10 tablets |
What are the side effects of Onglyza 5
Onglyza exhibits favorable safety characteristics in clinical trials. However, it may cause side effects, including:
- Upper respiratory tract infections
- Headache
- Dizziness
- Urinary tract infections
- Peripheral edema
- Low blood sugar (rare)
These adverse effects are typically mild and resolve without medical intervention as treatment continues. If they do not, consult a doctor.
Safety Advice
Liver disease
Patients with mild to moderate liver impairment usually don't require dose modifications. Severe hepatic dysfunction may necessitate careful monitoring and potential dosage reduction. Regular liver enzyme assessment is recommended during treatment. Consult a doctor before use.
Kidney impairment
A dose reduction to 2.5 mg daily is required for moderate to severe kidney disease. Patients with end-stage renal disease need specialized medical supervision. Creatinine clearance values determine appropriate dosing strategies. Consult a doctor before use.
Pregnant and breastfeeding women
Onglyza safety during pregnancy hasn't been established through adequate clinical studies. Insulin therapy remains preferred for gestational Diabetes management. Breastfeeding mothers should consult healthcare providers before using this medication.
Avoid
Alcohol consumption should be moderate to prevent unpredictable blood glucose fluctuations. Avoid skipping meals, as this may affect medication efficacy. Certain antibiotics and antifungal medications may require dosage adjustments when used concurrently.
FAQs
Does Onglyza 5 cause weight gain like other Diabetes medications?
No, Onglyza is generally weight-neutral, meaning it doesn't typically cause significant weight gain or loss. Some patients may experience slight weight reduction due to improved glucose control. This makes it advantageous for overweight diabetic patients.
Can I take Onglyza 5 if I have a history of Pancreatitis?
Patients with previous Pancreatitis should use Onglyza with extreme caution. DPP-4 inhibitors have been associated with rare cases of acute Pancreatitis. Immediate medical evaluation is necessary if severe abdominal pain develops during treatment.
How quickly does Onglyza 5 start working to control blood sugar?
Onglyza begins working within hours of administration, but noticeable improvements in blood glucose levels typically occur within 1-2 weeks. Maximum therapeutic effects are usually achieved after 4-6 weeks of consistent daily use.
Is it safe to drive while taking Onglyza 5?
Yes, Onglyza rarely causes Hypoglycemia when used alone, so driving is generally safe. However, when combined with Insulin or Sulfonylureas, Hypoglycemia risk increases. Monitor blood sugar levels and recognize warning signs before driving.
What should I tell my doctor before starting Onglyza 5 treatment?
Inform your doctor about all current medications, supplements, and medical conditions. Specifically, mention any kidney problems, liver disease, heart conditions, or history of Pancreatitis. This information helps determine if Onglyza is appropriate for you.