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Vargatef 100 Mg soft capsules
What is Vargatef 100 Mg soft capsules
Vargatef 100 mg soft capsules contain the active ingredient Nintedanib, which is classified as a tyrosine kinase inhibitor. This medication is primarily used to treat adults with Non-Small Cell Lung Cancer (NSCLC), specifically the adenocarcinoma subtype, when the cancer is locally advanced, metastatic, or locally recurrent.
Nintedanib works by blocking the activity of certain enzymes known as tyrosine kinases. These enzymes are involved in processes that promote cancer cell growth and the formation of new blood vessels that supply tumor cells. By blocking these enzymes, Vargatef helps slow down the progression of cancer by limiting its ability to grow and spread and prolonging survival in affected patients.
Special precautions must be taken when using Vargatef. The medication should be taken in combination with Docetaxel, starting on day two of a 21-day treatment cycle. Patients must not take Vargatef on the same day as Docetaxel. Regular monitoring of liver function is necessary, as Nintedanib can cause liver enzyme elevations, leading to potential liver injury. Additionally, patients should be cautious about gastrointestinal side effects, particularly diarrhea, which can lead to dehydration and electrolyte imbalances.
Few patients face negative interactions while taking Vargatef with other medications that could affect liver function or those that increase the risk of bleeding. Therefore, patients must inform their healthcare providers about all their medicines to avoid adverse effects.
This medication is manufactured and marketed by Boehringer Ingelheim.
What are the benefits of Vargatef 100 Mg soft capsules
Vargatef 100 mg soft capsules containing Nintedanib's active ingredient offer several benefits in treating non-small cell lung cancer (NSCLC). Primarily, it is used in combination with Docetaxel for adults with locally advanced, metastatic, or recurrent NSCLC of adenocarcinoma histology after first-line chemotherapy. This combination has been shown to significantly improve progression-free survival and overall survival compared to Docetaxel alone.
Vargatef helps patients with advanced lung cancer, offering a targeted approach that can improve outcomes when combined with other therapies. Additionally, it is generally well-tolerated, although some patients may experience manageable side effects such as nausea and diarrhea.
How to take Vargatef 100 Mg soft capsules
Vargatef soft capsules are prescription-based and should be taken as per a healthcare professional's instructions.
The general guidelines for taking this medication are listed below:
- Swallow a whole capsule with a glass of water without crushing, breaking open, or chewing it.
- Generally taken twice daily after food.
- Do not take more than twice in 24 hours.
- Vargatef soft capsules can be taken with or without food, but for optimal effectiveness, they must be taken consistently at the same time each day.
Strengths and Substitutes
Cheapmedicineshop provides different substitutes for the Vargatef 100 Mg soft capsules:
| $468.80/ 10 capsules |
What are the side effects of Vargatef 100 Mg soft capsules
Like any medication, Vargatef 100 mg may cause some side effects. These adverse effects are temporary and will subside as your body adjusts.
The side effects of using Vargatef 100 mg are as follows
- Diarrhea
- Nausea
- Abdominal pain
- Loss of appetite
- Fatigue
- Weight loss
- Headaches
Safety Advice
Liver disease
Vargatef 100 mg has not been shown to have adverse effects in patients with liver conditions, so it is safe for use. However, seeking medical advice from professionals is advised.
Kidney impairment
People with kidney problems can use these capsules, as they have no known effects on kidney function. However, it is recommended that they seek medical advice from professionals.
Pregnant and breastfeeding women
Limited data on its safety during pregnancy exist. However, this medication is recommended not to be used during pregnancy. It is also not recommended to prescribe this medication to breastfeeding women.
Avoid
Avoid consuming alcohol while taking Vargatef 100 mg, as it might show some adverse side effects and might impact the effectiveness of the medicine. Consult your healthcare provider for more specialized advice and suggestions.
FAQs
What are the uses of Vargatef 100 Mg soft capsules?
Vargatef 100 mg soft capsules, containing Nintedanib, are primarily used in combination with Docetaxel to treat adults with locally advanced, metastatic, or recurrent non-small cell lung cancer (NSCLC) of adenocarcinoma histology after prior chemotherapy.
How Vargatef 100 Mg soft capsules works?
Vargatef 100 mg soft capsules contain Nintedanib, a tyrosine kinase inhibitor that blocks multiple receptors, including VEGFR, PDGFR, and FGFR. Inhibiting these pathways reduces tumor growth and angiogenesis, slowing cancer progression, particularly in non-small cell lung cancer.
What should I do if I miss a dose of Vargatef?
If you miss a dose of Vargatef (Nintedanib), skip the missed dose and take your next dose at the regular scheduled time. Do not double the dose to compensate for the missed one. Always follow your prescribed dose schedule for safety and effectiveness.
Can Vargatef be taken with other medications?
Yes, Vargatef (Nintedanib) can be taken with other medications, but caution should be exercised. Monitoring for any signs of side effects is essential during combination therapy to avoid any type of complications.
How long can I expect to be on Vargatef treatment?
Treatment with Vargatef typically involves multiple cycles, often starting with a combination of Vargatef and Docetaxel for about 21 days per cycle. After completing several cycles, patients may continue Vargatef alone as long as it remains effective and manageable regarding side effects.