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Vargatef 500 Mg soft capsules
What is Vargatef 500 mg soft capsules
Vargatef 500 mg soft capsules primarily treat Idiopathic Pulmonary Fibrosis (IPF). IPF occurs when the tissue surrounding the air sacs, or alveoli, in the lungs becomes stiff and thick for unknown reasons. It also treats advanced non-small cell Lung Cancer (NSCLC).
It contains Nintedanib, which belongs to the medication class of kinase inhibitors. Boehringer Ingelheim Pharmaceuticals manufactures this medication. Nintedanib is a small-molecule tyrosine kinase inhibitor that competitively inhibits non-receptor tyrosine kinases (nRTKs) and receptor tyrosine kinases (RTKs).
It targets RTKs like PDGFR, FGFR, and VEGFR, which are involved in lung fibrosis and cancer cell growth. Binding these receptors prevents them from sending signals that promote cell growth, division, and tissue scarring.
Nintedanib inhibits nRTKs such as Src and Lyn to reduce fibrosis and abnormal cell activity. This dual mechanism slows down the progression of IPF. This active ingredient also prevents the growth of cancerous cells in Lung Cancer patients by interfering with the blood supply that supports tumor growth.
Take Vargateg 500 mg capsules as your doctor prescribes in the dose and duration. If you have missed a capsule, kindly take it as soon as you recall. However, you can skip the missed capsule and follow your routine. Do not double up the doses to compensate for the missed one.
What are the benefits of Vargatef 500 mg soft capsules
Nintedanib blocks tyrosine kinase enzymes, which block the signals that promote fibrosis and tumor growth. This helps decrease fibrous tissue forming in the lungs. This action stops the symptoms of lung disease from getting worse.
The Vargatef 500 mg soft capsules benefits are as follows:
- Anti-cancer treatment: These help slow tumor progression in non-small cell Lung Cancer.
- Targeted therapy for lung conditions: It inhibits pathways that cause lung fibrosis and Cancer cell growth.
How to take Vargatef 500 mg soft capsules
These anti-cancer treatment capsules are prescription-based and must be taken when prescribed by a healthcare professional. Here are some instructions on its usage:
- You can take this Vargatef capsule in the morning and evening at a fixed time.
- Swallow the capsules with water; do not chew, crush, split, or break it.
- Take the Vargatef soft capsules with food to minimize gastrointestinal side effects.
- Take 2 capsules in 24 hours. Your doctor can adjust the Vargatef dose according to your condition; hence, abide by the dose and duration they provide.
Strengths and Substitutes
Vargatef 500 is also available in a lower strength of 100 mg. Our online pharmacy, Cheap Medicine Shop, offers affordable substitutes.
| $225 per 10 tablets |
Safety Advice
Liver disease
Use Nintedanib with caution in patients with liver conditions as it is primarily metabolized in the liver. Dose adjustments may be needed; hence, consult a doctor.
Kidney impairment
Patients with kidney conditions can use this medicine. However, exercise caution for individuals with severe kidney impairment. Hence, consult your doctor for personalized advice.
Pregnant and breastfeeding women
Avoid the use of Vargatef capsules in pregnant and nursing women as it may pose potential risks to the unborn/developing baby. Hence, consult a doctor before use.
Avoid
Limit or avoid consuming alcohol as it can lead to potential complications. Consult your doctor for personalized advice.
FAQs
Who can use Vargatef 500 mg soft capsules?
Vargatef 500 mg soft capsules can be used by individuals with advanced, metastatic, or locally recurrent non-small cell Lung Cancer (NSCLC) of adenocarcinoma type. It is used with Docetaxel after first-line chemotherapy. Consult your doctor for personalized advice.
Are there any drug interactions with Vargatef 500 mg soft capsules?
Yes, Vargatef Soft Capsules may interact with blood thinners (e.g., Warfarin), CYP3A4 inhibitors (e.g., Ketoconazole), CYP3A4 inducers (e.g., Rifampin), and certain antibiotics. These interactions can increase the side effects or reduce its effectiveness. Always consult your doctor before use.
Is Nintedanib a chemotherapy drug?
No, Nintedanib is not a traditional chemotherapy drug but a targeted therapy, specifically a tyrosine kinase inhibitor. It is used in combination with chemotherapy for NSCLC and alone for IPF and other fibrotic lung diseases.
Who should not use Nintedanib?
Nintedanib should not be used by individuals with bleeding disorders or allergies to its ingredients. Patients taking strong anticoagulants should consult a doctor, as interactions may increase complications. Hence, consult a doctor for personalized advice.
How should I store Vargatef 500 mg soft capsules?
Store Vargatef 500 mg soft capsules at room temperature below 30°C in a dry place, away from moisture and direct sunlight. Keep the Vargatef capsules in their original packaging and out of reach of children and pets.