Arvast-CF Capsule DR

What is Arvast-CF DR

Arvast-CF DR is a combination medication used to treat Mixed Dyslipidemia in adults at high risk for cardiovascular events. Its primary ingredients are Fenofibrate (135mg) and Rosuvastatin (10mg), which belong to the fibrate and statin classes of lipid-lowering medications, respectively. The DR (Delayed Release) formulation ensures optimal absorption while minimizing digestive side effects.

This dual-action medication effectively reduces LDL (bad) cholesterol and triglycerides while increasing HDL (good) cholesterol levels. Arvast is prescribed when diet, exercise, and single-drug therapy are insufficient to achieve target lipid levels. Common side effects may include muscle pain, fatigue, headache, and digestive discomfort.

Regular liver function monitoring and muscle symptoms are essential during treatment. Intas Pharmaceuticals Ltd is the leading manufacturer of Arvast-CF DR, ensuring consistent quality and efficacy in this advanced lipid management solution.

What are the benefits of Arvast-CF DR

Arvast-CF DR combines the powerful actions of Fenofibrate and Rosuvastatin to deliver comprehensive lipid management. Rosuvastatin works by inhibiting HMG-CoA reductase, an enzyme crucial for cholesterol production in the liver, thereby effectively reducing LDL cholesterol levels.

Fenofibrate activates Peroxisome Proliferator-Activated Receptors (PPARs), which enhance the breakdown of triglycerides and increase HDL cholesterol production.

The delayed-release formulation offers enhanced benefits:

• Superior reduction of LDL cholesterol compared to single-agent therapy.
• Significant decrease in triglyceride levels, particularly beneficial for people with Mixed Dyslipidemia (high LDL cholesterol and triglycerides with low HDL).
• Substantial increase in beneficial HDL cholesterol.
• Improved cardiovascular outcomes and reduced risk of Atherosclerosis (hardening of arteries due to plaque buildup).
• Better gastrointestinal tolerance due to the delayed-release technology.

It is crucial to note that Arvast should be used as part of a comprehensive approach to cardiovascular health that includes appropriate dietary measures and regular physical activity.

How to take Arvast-CF DR

Arvast-CF is a prescription medication that should be taken as per your doctor's instructions. Here are the general guidelines:

• Take a capsule once daily, preferably in the evening.
• Swallow the capsule whole with water. Do not crush or open the capsule, which may affect the delayed-release properties.
• It may be taken with or without food, but taking it consistently with respect to meals is recommended.
• Do not exceed 1 Arvast capsule in 24 hours unless specifically directed by your doctor.

Strength and substitutes

The strengths and substitutes available for Arvast-CF DR are:

View all substitutes

What are the side effects of Arvast-CF DR

Arvast capsule is generally well-tolerated. However, it may cause side effects, including:

• Muscle pain, tenderness, or weakness
• Headache and dizziness
• Nausea, indigestion, or abdominal discomfort
• Elevated liver enzymes
• Fatigue or weakness

These side effects mostly do not require medical consultation and often diminish as your body adjusts to the medication. However, severe muscle pain, unexplained weakness, fever, or dark-colored urine should be reported to your doctor immediately as they may indicate a rare but serious condition called Rhabdomyolysis.

Safety Advice

Liver disease

The liver primarily metabolizes Arvast. Those with active liver disease or unexplained persistent elevations of serum transaminases should not take this medication. Regular liver function tests are recommended, especially during the first 12 months of treatment.

Kidney impairment

Patients with moderate kidney impairment should use Arvast with caution, and dosage adjustments may be required. During treatment, regular monitoring of kidney function and creatine kinase levels is recommended.

Pregnant and breastfeeding women

Arvast is strictly contraindicated during pregnancy, as statins may harm fetal development. Women should use contraception during treatment and for one month after stopping. It is also not recommended during breastfeeding, as its ingredients may pass into breast milk and affect the infant.

Avoid

Avoid grapefruit products, which can raise Rosuvastatin levels and cause side effects. Limit alcohol to reduce liver risks. Consult your doctor before combining it with other cholesterol-lowering medications.