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Januvia 25 Mg
What is Januvia 25 mg
Januvia 25 mg is an oral antidiabetic medication that promotes a balanced blood sugar level within a healthy range in patients with Type 2 Diabetes Mellitus. It contains Sitagliptin (25 mg), an FDA-approved active ingredient that helps lower blood glucose levels in these patients. MSD Pharmaceuticals Pvt Ltd manufactures the product.
Sitagliptin helps lower blood sugar by blocking the DPP-4 enzyme. This increases hormones that make the pancreas release more insulin and reduces the sugar made by the liver. Januvia 25 mg can be taken alone or with other diabetes medicines. However, it is not for Type 1 Diabetes or Diabetic Ketoacidosis.
The most common side effect of Januvia 25 mg is headache, which will disappear as the body adjusts to the medication. Some other common side effects include sneezing, sore throat, and runny or stuffy nose.
Hypoglycemia (low blood sugar levels) can become a factor when the medication is combined with other diabetes medications like Insulin and Sulfonylureas. Alcohol affects blood glucose levels, which increases the risk of Hypoglycemia (low blood sugar levels) and Hyperglycemia (high blood sugar levels). Other significant interactions include diseases like renal (kidney) and liver dysfunction, heart failure, and pancreatitis.
Lifestyle choices are essential to managing Diabetes. As the doctor recommends, incorporating a healthy diet and exercise into daily life, along with medication, can promote better Diabetes management.
What are the benefits of taking Januvia 25 mg
Januvia 25 mg provides several benefits for patients with Type 2 Diabetes Mellitus:
- It helps lower and maintain stable blood sugar levels.
- Stable blood sugar control lowers the risk of complications like kidney issues, nerve damage, vision problems, and heart disease.
- It blocks the DPP-4 enzyme, which raises incretin hormone levels—these hormones increase insulin production after eating and decrease the liver's sugar output.
How to take Januvia 25 mg
Januvia 25 mg is a prescription-based medication that must be taken per the doctor's instructions. Here are some general guidelines for this medication:
- The dose should be taken at a scheduled time daily as directed by your doctor.
- Swallow the tablet as a whole with water. Do not chew or crush it.
- You can take Januvia 25 mg with or without food.
- It should not be taken more than once daily.
Strengths and Substitutes
There are strengths and substitutes available at Cheap Medicine Shop:
| $16.3/10 pills | |
| $16.3/10 pills |
What are the side effects of Januvia 25 mg
Like any medication, Januvia 25 mg can cause side effects. These side effects are mild and tend to disappear as the body adjusts. However, consult a doctor immediately if the symptoms continue or worsen.
- Headache
- Sneezing
- Sore throat
- Stuffy or runny nose
- Hypoglycemia (low blood sugar levels)
Safety advice
Liver disease
Limited human studies suggest that Januvia 25 mg (Sitagliptin) is generally safe for patients with liver dysfunction. However, consult a doctor for precautionary measures.
Kidney impairment
For patients with kidney impairment, doctors should assess their kidney function before starting the treatment with Januvia 25 mg, as they may require dose adjustment.
Pregnant and breastfeeding women
Januvia 25 mg is not generally recommended for pregnant women as limited human studies have shown a potential risk to the fetus. Consult a doctor to weigh the benefits from the risks. Similarly, breastfeeding women should consult a doctor for any treatment with the medication.
Avoid
Alcohol consumption can alter blood glucose levels, causing low (Hypoglycemia) or high (Hyperglycemia) blood sugar levels, depending on how much or often one drinks. Similarly, a change in blood glucose level can affect one's driving ability.
FAQs
How long does Januvia stay in your system?
Januvia 25 mg (Sitagliptin) has a half-life of about 12 to 14 hours, meaning it takes that long for half of the medication to leave your body. Typically, it takes around 5 to 7 half-lives for a drug to be nearly fully cleared.
What is the recommended dosage of Januvia?
Your doctor should always determine the appropriate Januvia dosage based on your health and medical history. The usual dose is 100 mg daily, but it's reduced to 50 mg for moderate and 25 mg for severe kidney impairment. Your doctor will assess your kidney function and overall health to prescribe the safest and most effective dosage.
Will I lose weight while on Januvia 25 mg?
No, clinical studies have not shown weight loss as a common side effect of Januvia 25 mg. Some people may experience slight weight changes, which are usually insignificant and not directly attributed to the medication.
Can I take Metformin and Januvia together?
Yes, you can take Metformin and Januvia together. Januvia and Metformin are not known to interact with each other. Doctors usually prescribe them together to promote a stable blood glucose level in Type 2 Diabetes Mellitus patients.
Is there a generic brand for Januvia?
Januvia is available as a brand-name medication and not in a generic form. It contains the active salt Sitagliptin, a DPP-4 Inhibitor. Its main patent expires in November 2026, after which generics may become available. Although a Sitagliptin-based drug called Zituvio has been approved, it is not considered a direct generic substitute for Januvia.