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Meslataj DR 400 mg is a delayed-release oral tablet used to treat inflammatory bowel diseases such as Ulcerative Colitis and Crohn's ileo-colitis. Its active salt is FDA-approved Mesalamine (also called Mesalazine) 400 mg. It belongs to the aminosalicylate anti-inflammatory drug class and is manufactured by Taj Pharmaceuticals Ltd under GMP standards.
Mesalamine works locally in the intestinal lining by minimizing the production of inflammatory substances, such as prostaglandins and leukotrienes. This helps control inflammation, heal the bowel lining, and prevent disease flare-ups. It is mainly used for mild to moderate ulcerative colitis and for maintaining remission in Crohn's Ileo-colitis.
Tablets should be swallowed whole with water and not crushed or chewed. Adults usually take 2.4 gm daily for active disease and 1.2-2.4 gm daily for maintenance, either once daily or in divided doses. Drink plenty of fluids and continue treatment as prescribed. If a dose is missed, take it when remembered unless it is close to the next dose. Do not double doses. In case of overdose, seek emergency care immediately.
Common side effects of this anti-inflammatory are headache, nausea, abdominal pain, diarrhea, and gas. Get medical help for allergic reactions, severe abdominal pain, bloody stools, jaundice, or reduced urine output. Take caution in patients with kidney or liver disease and in elderly patients. Avoid if allergic to salicylates. It may interact with azathioprine, warfarin, and NSAIDs.
Store at 20-25°C, away from heat, moisture, and light, in the original pack.
Meslataj DR 400 is a delayed-release Mesalamine tablet used to manage Inflammatory Bowel Diseases (IBD) such as Ulcerative Colitis. It works directly in the intestine to control inflammation and support long-term gut health.
The benefits of taking Meslataj DR 400 include reducing bowel inflammation and easing symptoms like abdominal pain, diarrhea, rectal bleeding, and urgency. It helps heal the intestinal lining and is effective for both treating active flare-ups and maintaining remission, lowering the risk of future relapses.
Its delayed-release formulation delivers Mesalamine directly to the intestinal lining, minimizing widespread side effects compared to systemic steroids. Regular use can improve digestion, daily comfort, and overall quality of life in people with mild to moderate ulcerative colitis and Crohn's Ileo-colitis when taken as prescribed.
Meslataj DR 400 is a prescription-based medication that patients should take under the guidance of a healthcare professional. However, one should follow general guidelines to achieve optimal results. They are:
Currently, only 400 mg of Meslataj DR is available at Cheap Medicine Shop. There are substitutes with the same active ingredient available, which can be suitable depending on your needs. Always consult a doctor before opting for any of these medications.
| Mesacol 400 mg | $4.80/10 pills |
| Mesacol 800 mg | $5.90/10 pills |
Meslataj DR 400 is generally well tolerated when taken as prescribed. However, you may still experience some side effects, especially in the beginning. For treatment, they are usually mild and will go away as your body adjusts to the medication. Common Meslataj DR 400 side effects include:
However, if these effects continue or worsen, consult your doctor immediately.
Liver Disease
Patients with liver disease should use Meslataj DR 400 with caution, as dose adjustments may be needed due to the potential for liver function abnormalities. Liver enzymes should be monitored, and a doctor should be consulted if symptoms such as jaundice or unusual fatigue occur.
Kidney Impairment
Those with kidney impairment should also use this medicine carefully. It is not prescribed for patients with severe renal failure because of the risk of nephrotoxicity or interstitial nephritis. Regular kidney function tests, like serum creatinine, are essential before and during treatment.
Pregnant and Breastfeeding women
Pregnant women should consult their doctor before using Meslataj DR 400, as animal studies suggest potential fetal risk, though human data are limited. The medicine should only be used if the benefits outweigh the risks. Breastfeeding mothers should be cautious because the drug may pass into breast milk and cause diarrhea in the infant; close monitoring or alternative treatment may be necessary.
Avoid
Avoid taking this medicine if you are allergic to Mesalamine. Avoid alcohol as it can irritate the gut, worsen Inflammatory Bowel Disease (IBD) symptoms, and potentially interfere with the medication's effectiveness, increasing side effects like liver issues.
Meslataj DR 400 should be avoided by anyone who is allergic to salicylates or aspirin, has severe kidney failure, active pyloric stenosis, or blood disorders such as aplastic anemia. Treatment should be stopped immediately if unexplained bleeding, bruising, fever, sore throat, or severe rash occurs, and medical attention should be sought.
Foods that may worsen ulcerative colitis symptoms include spicy foods, high-fat fried foods, dairy, alcohol, caffeine, and processed foods. Avoiding these can help reduce inflammation, diarrhea, and abdominal discomfort during flare-ups.
The delayed-release (DR) formulation in Meslataj DR 400 mg ensures that Mesalamine is released mainly in the terminal ileum and colon, where inflammation from Ulcerative Colitis occurs. This targeted delivery improves effectiveness and reduces side effects compared to early absorption in the stomach or small intestine.
Yes, Mesalazine can affect the liver, but it is rare. It may cause elevated liver enzymes or, in very rare cases, hepatitis. Patients with liver dysfunction should use it with caution, and liver function should be monitored during treatment.
When taking mesalamine, avoid alcohol, aspirin, and other salicylates, as they can increase side effects. Certain medications, such as NSAIDs, warfarin, and azathioprine, may interact with mesalamine. Do not use it in severe kidney failure, active pyloric stenosis, or specific blood disorders, and always inform your doctor about all medicines you are taking.
Yes, Meslataj DR 400 helps heal the intestinal lining by reducing inflammation in the colon and rectum. It promotes mucosal healing, relieves symptoms, and helps prevent flare-ups in Ulcerative Colitis and Crohn's ileo-colitis.
Yes, the Meslataj DR 400 can often be used with biologics such as Infliximab or immunosuppressants such as Tacrolimus under a doctor's supervision. Combining therapies may help control inflammation and maintain remission, but careful monitoring is needed for potential interactions and side effects.
