Humalog Mix 25 Kwikpen 100IU/ml

What is Humalog Mix 25 KwikPen

Humalog Mix 25 KwikPen is a biphasic Insulin analog suspension used to treat Diabetes Mellitus in adults who require Insulin for blood glucose control. It contains a mixture of 25% Insulin Lispro (a rapid-acting Insulin analog) and 75% Insulin Lispro Protamine suspension (an intermediate-acting Insulin). Each KwikPen contains 3 ml of suspension with a concentration of 100 IU/ml (international units per milliliter).

Eli Lilly and Company is the renowned manufacturer of Humalog KwikPen, ensuring consistent quality and reliable performance. The pre-filled disposable pen device comes ready to use and eliminates the need for vial and syringe preparation.

Common side effects include Hypoglycemia, injection site reactions, and lipodystrophy. Store unused pens in a refrigerator (2°C to 8°C), do not freeze, and keep away from direct heat and light. After first use, the pen can be stored at room temperature (below 30°C) for up to 28 days. Discard the pen 28 days after the first use, even if Insulin remains. Protect from extreme temperatures and direct sunlight.

What are the benefits of Humalog Mix 25 KwikPen

Humalog KwikPen works through a dual-action approach to blood glucose management. The rapid-acting component (25% Insulin Lispro) begins working within 15 minutes of injection to cover mealtime glucose spikes, while the intermediate-acting component (75% Insulin Lispro Protamine) provides up to 24 hours of basal Insulin coverage.

The benefits of Humalog Mix 25 KwikPen include:

• Used for Type 1 and Type 2 Diabetes.
• Convenient pre-filled, disposable pen device requiring no refrigeration after first use.
• Rapid onset of action to control post-meal glucose excursions.
• Extended duration for basal Insulin coverage.
• Easy-to-use dial mechanism for precise dosing.
• Discreet, portable design for on-the-go administration.
• Reduced risk of medication errors compared to vial and syringe administration.

It is crucial to note that individual responses to Insulin therapy vary, and dose adjustments should be made based on regular blood glucose monitoring and in consultation with healthcare providers.

How to take Humalog Mix 25 KwikPen

Humalog KwikPen is a prescription medication that should be taken as per your doctor's instructions. If you are not well-trained to self-administer, ask a medical professional for help. Here are the general guidelines:

• Typically administered twice daily, 15 minutes before morning and evening meals.
• Resuspend Insulin by gently rolling the pen between palms and inverting the pen at least 10 times before each injection.
• Inject subcutaneously, i.e. under the skin, in the abdomen, thigh, upper arm, or buttocks. Attach a new needle before each injection and perform a safety test (2 units). Rotate injection sites to prevent lipodystrophy. Dispose of used needles properly in a sharps container.
• Do not exceed the prescribed dosage.

Strength and substitutes

The strengths and substitutes available for Humalog Mix 25 KwikPen are:

View all substitutes

What are the side effects of Humalog Mix 25 KwikPen

Humalog is generally well-tolerated when used correctly. However, it may cause side effects, including:

• Hypoglycemia (low blood sugar)
• Injection site reactions (redness, swelling, itching)
• Lipodystrophy (changes in fat tissue at injection sites)
• Weight gain

These adverse effects typically require monitoring but not discontinuation of therapy. Hypoglycemia should be treated promptly with fast-acting carbohydrates followed by a snack or meal if needed.

Safety Advice

Liver disease

Patients with hepatic impairment may experience altered Insulin metabolism, potentially requiring dosage adjustments. More frequent blood glucose monitoring is recommended in these patients. Regular liver function tests should be performed to assess disease progression and adjust Insulin therapy accordingly.

Kidney impairment

Due to reduced Insulin clearance, Insulin requirements may decrease in people with renal impairment. Patients with kidney disease should monitor blood glucose levels more frequently and may need dosage reductions. Careful titration under medical supervision is essential to prevent Hypoglycemic episodes.

Pregnant and breastfeeding women

Humalog Mix 25 can be used during pregnancy when clinically indicated, but Insulin requirements typically change throughout pregnancy. Strict glucose control is essential to prevent complications. First-trimester requirements may decrease, while second- and third-trimester needs often increase. Breastfeeding mothers may need to adjust Insulin doses or meal timing to prevent Hypoglycemia. Always consult a doctor before use.

Avoid

Alcohol without food or insulin adjustment increases Hypoglycemia risk, especially when combined with certain medications like beta-blockers or MAO inhibitors. Extreme temperatures can reduce insulin effectiveness. Sharing insulin pens, even with new needles, risks infection. Vigorous exercise without adjusting insulin or carbs can also cause low blood sugar.